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目的观察采用普罗帕酮(商品名:心律平)急救阵发性室上性心动过速(PSVT)患者的复律及用药安全性情况。方法 64例阵发性室上性心动过速患者为研究对象,按随机排列表法分为对比组和观察组,每组32例。对比组采用胺碘酮治疗,观察组采用普罗帕酮治疗,以患者用药后心率降至100次/min以下为复律标准,记录两组复律成功率及患者复律用时,同时对用药所致不良反应进行统计。结果观察组复律用时为(13.28±7.46)min、复律成功率为93.8%,对比组复律用时为(24.51±10.36)min、复律成功率为71.9%,观察组复律用时及复律成功率均优于对比组(P<0.05)。观察组不良反应发生率为31.3%,高于对比组的9.4%,差异具有统计学意义(P<0.05)。结论临床对阵发性室上性心动过速患者使用心律平治疗,复律成功率较高,作用快、复律用时短,但治疗过程中不良反应较多,用药时需注意安全。
Objective To observe the cardioversion and medication safety in patients with paroxysmal supraventricular tachycardia (PSVT) under propafenone (brand name: heart rhythm). Methods Sixty - four patients with paroxysmal supraventricular tachycardia were divided into control group and observation group according to randomized table method, with 32 cases in each group. The control group was treated with amiodarone. The observation group was treated with propafenone, and the heart rate was reduced to 100 times / min following the patient’s medication. The success rate of cardioversion and the patient’s cardioversion were recorded. At the same time, Cause adverse reactions to statistics. Results The duration of cardioversion in observation group was (13.28 ± 7.46) min, the success rate of cardioversion was 93.8%, the duration of cardioversion in control group was (24.51 ± 10.36) min, the success rate of cardioversion was 71.9% Law success rates were better than the control group (P <0.05). The incidence of adverse reactions in the observation group was 31.3%, which was higher than 9.4% in the control group, the difference was statistically significant (P <0.05). Conclusions The clinical treatment of patients with paroxysmal supraventricular tachycardia with heart rhythm treatment, high success rate of cardioversion, fast acting, short recovery time, but more adverse reactions during treatment, medication should pay attention to safety.