四十年代,青霉素治疗细菌性感染疾患取得惊人效果,五十年代又相继发现了链霉素、氯霉素、金霉素等。因此,有人进一步开展了从微生物产物中筛选抗肿瘤物质,至今,报导的(包括体内对动物实验肿瘤有抑制作用和体外有细胞毒作用者)已超过四百种,其中有不少有临床应用价值。微生物产生的有抗肿瘤活性的物质,叫做抗肿瘤抗菌素,本药的发展,使新抗菌素研究早已突破了抗菌的范围。目前,放线菌素D(更生霉 In the 1940s, penicillin treatment of bacterial infections achieved remarkable results. In the 1950s, streptomycin, chloramphenicol, and chlortetracycline were discovered in succession. Therefore, some people have further carried out the screening of anti-tumor substances from microbial products. So far, there have been more than 400 kinds of reported anti-tumor substances (including those having inhibitory effects on animal experimental tumors in vivo and cytotoxicity in vitro), many of which have clinical applications. value. Microorganisms produce anti-tumor activity substances called anti-tumor antibiotics. The development of this drug has enabled the research of new antibiotics to break through the scope of antibacterial. At present, actinomycin D