吗特灵在５１例恶性肿瘤中的应用山西省肿瘤医院（０３００１３）崔红莉，王永芳，李夏玲，康全秀我们对我院１９９２年４月～１９９３年４月５１例中晚期恶性肿瘤单纯应用吗特灵（ＡＦＴ）注射液治疗，收到较好的效果，现报告如下。资料与方法一、一般资料：本组５１例经细胞学或组织学证实。符合全国肿瘤学会统一诊断标准。５１例中男性３４例，女性１７例；年龄最小２５岁，最大７８岁，平均年龄为５９岁；其中食管癌１３例，胃癌１３例，肝癌１２例，大肠癌９例，肺癌４例。二、用药方法及剂量：根据患者的病情和个体差异，确定用药剂量。一般病人首先１０００ｍｇ加入５％葡萄糖５００ｍｌ静脉滴注。每分钟５０～６０滴，每日一次，连续３～４天观察无不良反应可增加药量，改为１５００ｍｇ加入葡萄糖５００ｍｌ葡萄糖静脉滴注，每日一次，累计药量为４５克为一疗程；用药前后常规检查肝肾功能和血常规，以及Ｂ超检查对照病灶缩小情况。结果一、治疗结果见表１。二、治疗中所引起的副反应见表２。以上副反应均在停药后自行缓解。讨论吗特灵的主要成份是苦参总碱，它是从豆科植物苦参中提取的纯中药制剂。该药原始作用是清热、燥湿、杀虫、利尿，近年来有文献报道具有抗癌，调节免疫机能，抗心律失 Application of Mottling in 51 Cases of Malignant Tumors Shanxi Provincial Tumor Hospital (030013) Cui Hongli, Wang Yongfang, Li Xia Ling, Kang Quanxiu We applied Metarin to 51 cases of advanced and advanced malignant tumors in our hospital from April 1992 to April 1993. (AFT) injection treatment, received good results, the report is as follows. Materials and Methods First, general information: 51 cases in this group were confirmed by cytology or histology. In line with the unified diagnostic criteria of the National Oncology Society. Among the 51 cases, there were 34 males and 17 females; the youngest was 25 years old, and the youngest was 78 years old, and the average age was 59 years old. Among them, there were 13 cases of esophageal cancer, 13 cases of gastric cancer, 12 cases of liver cancer, 9 cases of colorectal cancer, and 4 cases of lung cancer. Second, medication methods and dose: According to the patient’s condition and individual differences, determine the dose. The average patient is first intravenously infused with 1000 mg of 5% glucose 500 ml. 50 to 60 drops per minute, once a day, for 3 to 4 consecutive days to observe no adverse reactions can increase the dose, to 1500mg glucose glucose 500ml intravenous drip, once daily, the cumulative dose of 45 grams for a course of treatment; Routine examination of liver and kidney function and blood routine before and after administration, and B-mode ultrasonography to reduce lesions. Results 1. The treatment results are shown in Table 1. Second, the side effects caused by treatment are shown in Table 2. All the above side reactions were relieved after drug withdrawal. The main ingredient in the discussion of morphine is matrine, a pure Chinese medicine extracted from Sophora flavescens. The original role of the drug is heat, dampness, insecticidal, diuretic, in recent years has been reported in the literature with anti-cancer, regulate immune function, anti-arrhythmia