材料取自八例食管上皮增生,十四例食管癌患者的活检和手术标本。常规制备超薄切片,H-500电镜观察。结果如下:正常食管上皮细胞由丛底层,棘层(图1)到表层,上皮细胞逐次分化成熟、死亡、脱落。细胞亚结构随之发生改变,微绒毛、线粒体和核糖体的数量由多逐渐变少;张力微丝由少逐渐增多;桥粒在基层较少,棘层增多,至表层消失,核浆比值由大变小。 Materials from eight cases of esophageal epithelial hyperplasia, fourteen cases of esophageal cancer biopsies and surgical specimens. Conventional preparation of ultra-thin sections, H-500 electron microscopy. The results are as follows: normal esophageal epithelial cells from the bottom plexus, spinous layer (Figure 1) to the surface, epithelial cells gradually differentiated maturity, death, fall off. The number of microvilli, mitochondria and ribosomes gradually decreased from less to more; the number of tension microfilaments gradually increased from less to less; desmosomes increased less in the primary layer and disappeared in the surface layer, Bigger and smaller.