据Longeneker等报导,异丙基胺基乙醇对大鼠有胚胎毒样活性,它可影响子宫内膜而阻止胚胎发育,本身无激素样活性。Hetherington报导异丙基胺基乙醇能抑制小鼠蜕膜细胞的生长,从而引起胚胎死亡。我们认为本药合成路线简便,可望成为一种非甾体的催经止孕药,故进行了合成及药理研究。 According to reports by Longeneker et al., Isopropylaminoethanol has an embryonic toxicoid activity in rats, which can affect the endometrium and prevent embryonic development, with no hormone-like activity by itself. Hetherington reported that isopropylaminoethanol can inhibit the growth of mouse decidual cells, causing embryonic death. We believe that this drug synthesis route is simple and convenient, is expected to become a non-steroidal reminder by the pill, so the synthesis and pharmacological studies.