论文部分内容阅读
目的探讨难治性癫痫患者血清层粘连蛋白的表达。方法我院进行治疗的难治性癫痫患者病例和非难治性癫痫患者病例各35例,分别作为难治性组和非难治性组,同时回顾分析同期进行健康体检的健康志愿者30名,作为健康组。分别对3组患者进行血清层粘连蛋白含量测定。结果难治性组患者的层粘连蛋白检测结果明显高于非难治性组和健康组患者(P<0.05),具有统计学意义;非难治性组患者的层粘连蛋白检测结果明显高于健康组患者(P<0.05),具有统计学意义。结论在癫痫患者中层粘连蛋白的表达会出现明显增加的现象,并且在难治性癫痫患者的血清中层粘连蛋白的表达量的增加现象则会更加的明显,在今后的临床工作中应对其予以注意。
Objective To investigate the expression of serum laminin in patients with refractory epilepsy. Methods A total of 35 patients with refractory epilepsy and non-refractory epilepsy were treated in our hospital as refractory and non-refractory patients, respectively. At the same time, 30 healthy volunteers during the same period were retrospectively analyzed. Health group. Serum laminin levels were measured in 3 groups of patients respectively. Results The results of laminin in refractory group were significantly higher than those in non-refractory group and healthy group (P <0.05), with statistical significance; laminin in non-refractory group was significantly higher than that in healthy group Patients (P <0.05), with statistical significance. Conclusions The expression of laminin in epilepsy patients increases obviously, and the increase of laminin expression in sera of patients with intractable epilepsy will be more obvious, which should be paid attention to in future clinical work .