局限性前列腺癌的自然病程究竟多长还不明确。Whitmore(1984)发现在一组B期(T1-2)被延迟治疗的前列腺癌病人,长期生存而病变没有进展。他们以前曾经报告过一组病人,有的观察5年后才有转移。现在,对这类病人的随访长达10年以上。病人和方法:1978～1982年间,对172例新发现的、恶性度低的前列腺癌病人进行前瞻性研究。大部分病人肿瘤较小,也有的肿瘤较大。所有病人靠细胞学诊断,标本来自经直肠的细针穿刺。定期随访病人,常规的临床观察和血清酸性磷酸酶测定每3-6个月一次,骨扫描每12-18个月一次。死亡的原因和时间,来自病历和瑞典国家死亡登记处。死于前列腺癌 It is unclear how long natural history of localized prostate cancer is. Whitmore (1984) found that in a group of prostate cancer patients whose stage B (T1-2) was delayed, long-term survival did not occur. They had previously reported a group of patients, and some had only 5 years after the shift. Now, these patients have been followed up for more than 10 years. Patients and Methods: Between 1978 and 1982, prospective studies were performed on 172 newly diagnosed, less-malignant prostate cancer patients. Most patients have smaller tumors and some have larger tumors. All patients were diagnosed by cytology and the specimens were obtained from transrectal fine needle aspiration. Patients were followed up regularly, routine clinical observations and serum acid phosphatase measurements were performed every 3-6 months, and bone scans were performed every 12-18 months. The cause and time of death come from the medical record and the Swedish National Death Registry. Died of prostate cancer