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目的:了解晚期胆管癌姑息胆道引流的治疗效果,探讨晚期胆管癌的治疗方法。方法:分析经胆道引流术治疗的晚期胆管癌35例的临床资料。手术方式包括胆肠吻合术,胆肠置管搭桥引流,U管引流,单纯外引流,或两种术式联用。结果:77.1%术后两周内血清总胆红素下降50%以上。22.9%出现术后早期并发症,手术死亡率14.3%。术后随访:胆肠引流术9例,中位生存期11.3个月。U管引流7例存活1年以上。单纯外引流3例术后3个月内死亡。结论:胆道引流术是治疗晚期胆管癌的一种有效方法,可获良好的姑息治疗效果。
Objective: To understand the therapeutic effects of palliative biliary drainage in advanced bile duct cancer and explore the treatment of advanced cholangiocarcinoma. Methods: The clinical data of 35 patients with advanced cholangiocarcinoma treated with biliary drainage were analyzed. Surgical methods include biliary-enteric anastomosis, biliary bowel bypass, U-tube drainage, external drainage, or two surgical procedures. Results: 77.1% of total serum bilirubin decreased by more than 50% within two weeks after operation. 22.9% had early postoperative complications and the operative mortality rate was 14.3%. Postoperative follow-up: 9 cases with biliary bowel drainage had a median survival of 11.3 months. U tube drainage in 7 cases survived for more than 1 year. Simple external drainage in 3 cases died within 3 months after operation. Conclusion: Biliary drainage is an effective method for the treatment of advanced cholangiocarcinoma and can be used as a good palliative treatment.