目的:探讨组织细胞性坏死性淋巴结炎的临床特点及诊治结果。方法:对16例组织细胞性坏死性淋巴结炎进行回顾性分析。结果:16例中,曾有9例误诊,误诊率56.3 %,均经肾上腺皮质激素药物治疗后痊愈。结论:该病起病急,临床表现无特异性,易误诊,确诊需作局部淋巴结组织病理活检。对肾上腺皮质激素药物敏感,治疗结果呈良性自限性过程,预后好。 Objective: To investigate the clinical features and diagnosis and treatment of histiocytic necrotizing lymphadenitis. Methods: 16 cases of histiocytic necrotizing lymphadenitis were retrospectively analyzed. Results: Of the 16 cases, 9 cases were misdiagnosed and the rate of misdiagnosis was 56.3%. All of them were cured after treatment with adrenocorticotropic hormone. Conclusion: The disease onset acute, nonspecific clinical manifestations, easily misdiagnosed, diagnosed with local lymph node biopsy. Sensitive to adrenocorticotropic drugs, the treatment showed a benign self-limiting process, the prognosis is good.