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肿瘤发生的癌干细胞假说认为肿瘤组织是由处于各种分化等级的细胞组成的,其中的癌干细胞数量虽少,但在肿瘤的发生、恶化、转移中起重要作用。肝细胞癌作为最常见的恶性肿瘤之一,其中是否存在“肝癌干细胞”的问题一直倍受人们关注。该文介绍肝癌干细胞的研究情况。
Cancer stem cell hypothesis Hypothesis that the tumor tissue is composed of cells in a variety of differentiation levels, including a small number of cancer stem cells, but plays an important role in tumor occurrence, deterioration, metastasis. As one of the most common malignant tumors of hepatocellular carcinoma, the question of whether there is “liver cancer stem cells” has drawn much attention. This article describes the study of liver cancer stem cells.