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目的研究急性脑梗死患者高同型半胱氨酸血症(HHCY)和血浆纤维蛋白原(FIB)相关性。方法收集2014年8月~2015年6月在我院神经内科住院的急性脑梗死患者96例作为实验组。选取同期体检的非脑梗死者60例作为对照组，对比分析两组间同型半胱氨酸(HCY)和FIB的相关性。结果实验组FIB显著高于对照组(<0.01)。实验组HCY显著高于对照组(<0.01)。 HCY与FIB呈正相关(<0.05)。结论急性脑梗死患者与HHCY升高和FIB升高相关。 HCY升高与FIB水平相关，两者联合检测具有重要临床意义。“,”Objective To reseach the cor elation of hyperhomocysteinemia (HHCY)and plasma fibrinogen (FIB)in patients with acute cerebral infarction.Methods To col ect 96 patients with acute cerebral infarction from August 2014 to June 2015 in the department of neurology of my hospital,as experimental group,and 60 cases of hospital physical examination without cerebral infarction were selected as control group.The cor elation of homocysteine (HCY)and FIB between two groups were analysed.Results The FIB in experimental group was significantly higher than in control group ( <0.01).The HCY in experimental group was significantly higher than in control group ( <0.01).HCY and FIB was positively related ( <0.05).Conclusion Acute cerebral infarction is related to the higher HCY and higher FIB.The rise of HCY is related to the level of FIB,the joint detection has great clinical significance.