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目的 :探讨胃癌癌周肥大细胞 (MC)密度与淋巴结癌转移的关系。方法 :应用俾士麦棕法检测伴有淋巴结癌转移的 2 5 3例胃癌病例。结果 :1～ 6ILN病例MC密度高于≥ 7～ 15ILN病例 ,7～ 15ILN病例MC密度高于 >15ILN病例 ,P 均 <0 .0 1。≥ 5年生存年限的病例MC密度高于 <5年生存年限病例的MC密度 ,P <0 .0 1。 5年生存率 ,1～ 6ILN病例高于 7～ 15ILN病例 ,7～ 15ILN病例高于 >15ILN病例 ,P均 <0 .0 1;rs =-0 .2 5 7。结论 :胃癌癌周MC密度与ILN及 5年生存率相关 ,是反映胃癌预后的一个有价值的指标。
Objective: To investigate the relationship between peritumoral mast cell (MC) density and lymph node metastasis in gastric cancer. Methods: A total of 253 cases of gastric cancer with lymph node metastasis were detected by Bismarck-Brown method. Results: The density of MC in 1 ~ 6ILN cases was higher than that of ≥ 7 ~ 15ILN cases. The MC density in 7 ~ 15ILN cases was higher than that in> 15ILN cases, P <0.01. MC densities of patients with ≥ 5 years of survival were higher than those of patients with <5 years of survival, P <0.01. 5-year survival rate, 1 ~ 6ILN cases higher than 7 ~ 15ILN cases, 7 ~ 15ILN cases higher than> 15ILN cases, P <0.01; rs = -0.257. Conclusion: The correlation of MC density in gastric cancer with ILN and 5-year survival rate is a valuable indicator of the prognosis of gastric cancer.