论文部分内容阅读
目的观察应用椎体后凸成形术治疗脊柱转移瘤的疗效。方法共治疗29例患者76处脊柱转移瘤病灶,男11例,女18例,年龄30～82岁,平均63.7岁。影像学检查及术后病理证实有脊柱转移瘤。临床伴有明显持续性骨痛,症状持续时间为1～18个月,平均5.2个月。29例患者76处脊柱转移瘤病灶均给予椎体后凸成形术治疗。治疗前后观察疼痛强度的变化情况、患者的止痛药使用评分并行SF-12健康状况调查。结果29例患者76处病灶手术顺利完成。疼痛评分由治疗前的5.0～9.6,平均7.8±1.3减少为治疗后的2.8～5.5,平均3.9±0.9(P<0.01)。止痛药使用评分由治疗前的3～4,平均3.3±0.4,减少为治疗后的1～3,平均1.9±0.8(P<0.01)。SF-12健康调查评分治疗前为-17～-34,平均-29.1±4.3,治疗后为-15～-33,平均-22.6±3.8(P<0.05)。术后随访3～18个月,平均8.7个月,患者疼痛症状及生活质量较术前改善满意。结论应用椎体后凸成形术治疗脊柱转移瘤可有效的缓解疼痛,改善患者后期生活质量。
Objective To observe the curative effect of kyphoplasty on spinal metastases. Methods A total of 76 spinal metastases in 29 patients were treated, including 11 males and 18 females, aged from 30 to 82 years (average 63.7 years). Imaging examination and postoperative pathology confirmed spinal metastases. Clinical accompanied by significant persistent bone pain, symptoms duration of 1 to 18 months, an average of 5.2 months. Twenty-nine patients with spinal metastases lesions were given kyphoplasty. Before and after treatment to observe the changes in pain intensity, the patient’s pain medication use score parallel SF-12 health survey. Results The operation of 76 lesions in 29 patients was successfully completed. Pain scores decreased from 5.0 to 9.6 before treatment, with an average of 7.8 ± 1.3 to 2.8 to 5.5 after treatment, with an average of 3.9 ± 0.9 (P <0.01). Painkiller use scores from 3 to 4 before treatment, an average of 3.3 ± 0.4, reduced to 1 to 3 after treatment, an average of 1.9 ± 0.8 (P <0.01). The SF-12 health survey score was -17 to -34 before treatment, with an average of -29.1 ± 4.3 and -15 to -33 after treatment, with an average of -22.6 ± 3.8 (P <0.05). The patients were followed up for 3 to 18 months with an average of 8.7 months. The patients’ pain symptoms and quality of life were better than those before the operation. Conclusion The application of kyphoplasty in the treatment of spinal metastases can effectively relieve pain and improve the quality of life of patients in later stage.