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透射电子显微镜研究表明,质粒pBR322 DNA 分子中有一种特殊的拓扑结构因子,这种拓扑结构因子能阻止超螺旋扭力在整个分子内的传递.细胞内的巨大染色体DNA 可能被这种结构分隔成较小的环
Transmission electron microscopy studies have shown that there is a special topology of the pBR322 DNA molecule, a topological factor that prevents the transmission of supercoiled torsion throughout the molecule. Giant chromosomal DNA inside a cell may be separated into smaller loops by this structure