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目的观察奥美拉唑联用西沙必利治疗反流性食管炎的临床疗效。方法将92例经内镜证实为反流性食管炎的患者随机分为治疗组和对照组:治疗组口服奥美拉唑加西沙必利,对照组口服雷尼替丁加西沙必利,两组均治疗8周。结果治疗组总有效率为95.6%,对照组总有效率为71.7%,两组比较差异有统计学意义(P<0.05)。结论奥美拉唑联用西沙必利治疗反流性食管炎疗效显著。
Objective To observe the clinical efficacy of omeprazole combined with cisapride in the treatment of reflux esophagitis. Methods 92 patients with reflux esophagitis confirmed by endoscopy were randomly divided into treatment group and control group: omeprazole plus cisapride was administered to the treatment group, ranitidine plus cisapride was administered to the control group, Group were treated for 8 weeks. Results The total effective rate was 95.6% in the treatment group and 71.7% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion omeprazole combined with cisapride in the treatment of reflux esophagitis significant effect.