慢性鼻窦炎,鼻息肉通常伴有鼻道黏液分泌亢进、分泌物潴留,进而造成鼻黏膜水肿,窦口阻塞,加重病情发展。随着呼吸道高分泌疾病(如COPD、支气管扩张、肺囊性纤维病等)的深入研究发现,该类疾病的急性发作期或晚期阶段中黏液潴留,除黏蛋白的绝对量增多外,还与黏蛋白/水盐比例失衡 Chronic sinusitis, nasal polyps usually accompanied by hypertrophy of the nasal mucus secretion, retention of secretions, and then cause nasal mucosal edema, sinus obstruction, aggravating the disease progression. In-depth studies of respiratory and endocrine disorders (such as COPD, bronchiectasis, pulmonary cystic fibrosis, etc.) have found that mucus retention, in addition to an increase in the absolute amount of mucin, is associated with acute or late stages of the disease Mucin / water-salt imbalance