论文部分内容阅读
目的了解四川地区外阴营养不良的基本流行病学数据,同时比较其两种亚型(单纯性苔藓型和硬化性苔藓型)电生理治疗的可行性及效果。方法对2010~2015年在四川大学华西第二医院门诊诊断为外阴营养不良的患者进行横断面调查;同时采用前瞻性队列研究的方法,纳入2015年1~12月在本院经病理活检证实为外阴营养不良的患者26例(单纯性苔藓型18例和硬化性苔藓型8例),采集临床数据,包括瘙痒量表评分和皮肤状态评估,由专人采用统一方法进行电生理治疗,记录治疗前后疾病状态的变化。结果 (1)2010~2015年我院妇科门诊诊断为外阴营养不良的患者为33 859例,患病率为1.38%;(2)成都地区(13 870例,40.96%)及川南地区(6 333例,18.70%)患病人群明显多于其它地区;城镇患者(22 998例,67.92%)明显多于农村患者(10 861例,32.08%);(3)除了40~50岁年龄段,单纯性苔藓及硬化性苔癣患病率在其它不同年龄段间的差异均有统计学意义(P<0.05)。两组患者经电生理治疗后随访6~12个月,外阴皮肤颜色改善18例(69.23%),瘙痒评分改善22例(84.62%);其中单纯性苔藓组治疗有效率为88.89%(16例),硬化性苔藓组治疗有效率为50.00%(4例),两组间有效率的差异有统计学意义(P<0.01)。结论外阴营养不良在四川地区相对常见,且发病具有一定的区域差异;单纯性苔藓型患者更为年轻,且电生理治疗效果更好。
Objective To understand the basic epidemiological data of vulva dystrophy in Sichuan and to compare the feasibility and effect of electrophysiological treatment of two subtypes (simple moss and sclerosing moss). Methods A cross-sectional survey of patients with genital malnutrition diagnosed at the Second West China Hospital of Sichuan University from 2010 to 2015 was conducted. A prospective cohort study was conducted to assess the risk of genital malnutrition in our hospital from January to December 2015 Twenty-six patients with genital malnutrition (18 for simple moss and 8 for sclerosing moss) were enrolled in this study. Clinical data including scoring of pruritus and assessment of skin condition were collected. Electrophysiological treatments were performed by a single person using a uniform method. Before and after treatment Changes in disease status. Results (1) There were 33 859 cases diagnosed as vulvar dystrophy in our gynecology clinic from 2010 to 2015, the prevalence was 1.38%. (2) In Chengdu (13 870 cases, 40.96%) and in South Sichuan (22.998 cases, 67.92%) were significantly more than those in rural areas (10 861 cases, 32.08%); (3) In addition to the age group of 40 to 50 years, simple The prevalence of lichen and lichen sclerosus in other age groups were significantly different (P <0.05). The electrophysiological treatment was followed up for 6 to 12 months in both groups. The skin color of the vulva was improved in 18 cases (69.23%) and the pruritus score was improved in 22 cases (84.62%). The effective rate of the simple moss group was 88.89% (16 cases ), The effective rate of curing moss group was 50.00% (4 cases), the difference between the two groups was statistically significant (P <0.01). Conclusions Vulvar malnutrition is relatively common in Sichuan Province and has some regional differences in incidence. Simplex mosquito patients are younger and their electrophysiological effects are better.