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目的观察14C-尿素呼气试验(14C-UBT)检测幽门螺杆菌(HP)的临床应用。方法经胃镜确诊并利用14C-UBT检测HP患者836例其中癌症36例,十二指肠溃疡158例,胃溃疡146例,慢性浅表性胃炎263例,慢性萎缩性胃炎106例,正常胃黏膜127例。结果检测HP阳性率分别为94.4%、90.5%、72.6%、56.6%、27.4%、26.8%。结论 HP感染与胃炎、消化性溃疡、胃癌密切相关。14C-UBT具有无创伤、无痛苦、无交叉感染、准确、简便、快速、经济等优点。
Objective To observe the clinical application of 14C-urea breath test (14C-UBT) in detecting Helicobacter pylori (HP). Methods Totally 836 HP patients were diagnosed by gastroscope and 368 were diagnosed as HP, including 36 cases of cancer, 158 cases of duodenal ulcer, 146 cases of gastric ulcer, 263 cases of chronic superficial gastritis, 106 cases of chronic atrophic gastritis, 127 cases. Results The positive rates of detecting HP were 94.4%, 90.5%, 72.6%, 56.6%, 27.4%, 26.8% respectively. Conclusion HP infection is closely related to gastritis, peptic ulcer and gastric cancer. 14C-UBT with no trauma, no pain, no cross-infection, accurate, simple, fast, economical and so on.