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[期刊论文] 作者：Yingsi Zhou,Yajing Liu,Wenqin Ying,Ruiming Lv,Qimeng Zhao,Haibo Zhou,Erwei Zuo,Yidi Sun,Hui Yang,Changyang Zhou,
来源：蛋白质与细胞 年份：2021
Dear Editor,rnNewly discovered characteristics like “collateral effect” or trans-cleavage in CRISPR-Cas13 and CRISPR-Cas12 sys-tems have enabled their usage in nucleic acid detection(Gootenberg et al.2017,2018;Chen et al.2018).The col-lat......
[期刊论文] 作者：Changyang Zhou,Meiling Zhang,Yu Wei,Yidi Sun,Yun Sun,Hong Pan,Ning Yao,Wanxia Zhong,Yixue Li,Weiping,
来源：蛋白质与细胞 年份：2017
Dear Editor,There are hundreds of disease-causing single-gene mutations,mainly caused by single-nucleotide substitutions or point mutations rather than small in...
[期刊论文] 作者：Changyang Zhou,Xinde Hu,Cheng Tang,Wenjia Liu,Shaoran Wang,Yingsi Zhou,Qimeng Zhao,Qiyu Bo,Linyu Shi,,
来源：国家科学评论（英文版） 年份：2020
Age-related macular degeneration (AMD),characterized by the development of choroidal neovascularization (CNV),is a leading cause of vision deterioration in adul...
,Disruption of splicing-regulatory elements using CRISPR/Cas9 to rescue spinal muscular atrophy in h
[期刊论文] 作者：Erwei Zuo,He Li,Wenqin Ying,Yidi Sun,Lu-Lu Lai,Hai-Zhu Chen,Xin-Xin Guo,Qi-Jie Zhang,Shuang Wu,Changyang Zhou,
来源：国家科学评论（英文版） 年份：2020
We here report a genome-editing strategy to correct spinal muscular atrophy (SMA).Rather than directly targeting the pathogenic exonic mutations,our strategy em...
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