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[期刊论文] 作者:David J Mulholland, 来源:亚洲男性学杂志:英文版 年份:2012
[期刊论文] 作者:David J Mulholland, 来源:亚洲男性学杂志(英文版) 年份:2012
Prostate cancer remains a leaading cause of death in men in the United States.1,2 Treatment for advanced disease almost always includes androgen deprivation therapy (ADT)3 largely because the androgen receptor (AR) is expressed at......
[期刊论文] 作者:Mengmeng Liang,David J Mulholland, 来源:亚洲男性学杂志(英文版) 年份:2014
Cancer cells often depend on altered metabolism compared with their normal counterparts.1-4 As observed in 1924 by Otto Warburg,cancer cells show preferential glucose consumption by way of aerobic glycolysis while normal cells generally ass......
[会议论文] 作者:胡晓勇,傅强,Consuelo Garcia,David J Mulholland, 来源:泌尿生殖肿瘤华夏医学论坛2016暨长城国际泌尿男科转化医学论坛2016 年份:2016
蛋白磷酸酶2A(protein phosphatase 2 A,PP2A)信号轴对去势抵抗性前列腺癌(CRPC)的发生和发展具有重要调控作用。我们发现靶向作用于内源性PP2A抑制因子—SET(I2PP2A)可抑制去势抵抗前列腺癌进展。......
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