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Migration of smooth muscle cells from the arterial anastomosis of arteriovenous fistulas form neoint
[会议论文] 作者：Ming Liang,Junzhou Fu,Jizhong Cheng,
来源：2015肾脏病研究进展南方国际论坛暨广东省医学会肾脏病学学术年会 年份：2015
Aims :A major factor contributing to failure of arteriovenous fistulas (AVFs) is migration of smooth muscle cells into the forming neointima.The problem with identifying the origin of cells that const...
[会议论文] 作者：梁鸣,傅君舟,Jizhong Cheng,
来源：2015肾脏病研究进展南方国际论坛暨广东省医学会肾脏病学学术年会 年份：2015
目的 血管平滑肌细胞(SMCs)迁移、增殖是慢性肾脏病自体动静脉内瘘(AVF)内膜增生的重要病理基础.因此,抑制SMCs增殖及迁移是防治动静脉成形术后内膜增生再狭窄的有效策略.方法 采用肾大部分切除手术构建慢性肾脏病小鼠模型,行右侧颈总动脉-颈外静脉端端吻合术.1......
[会议论文] 作者：梁安霖,王韵,JizhongCheng,
来源：中华医学会第十七届骨科学术会议暨第十届COA国际学术大会 年份：2015
目的被动或主动活动是临床上减轻神经源性肌萎缩的主要方法,PI3K/Akt通路是调节骨骼肌萎缩和肥大的重要机制,而SGK1是Akt的姊妹,有54％的同源性,但其作用的下游底物和活化位点有所不同,故SGK1功能不同,且大部分未知。我们因此推测SGK1在神经源性肌肉萎缩中有一定......
RBP-Jk involved in neointema formation in Chronic Kidney Disease-Induced AVF Failure through regulat
[会议论文] 作者：Yun Wang,Anlin Liang,William E.Mitch,Jizhong Cheng,
来源：中国细胞生物学学会2013年全国学术大会 年份：2013
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RBP-Jk involved in neointema formation in Chronic Kidney Disease-Induced AVF Failure through regulat
[会议论文] 作者：Yun Wang,Anlin Liang,William E.Mitch,Jizhong Cheng,
来源：中国细胞生物学学会2013年全国学术大会 年份：2013
The most favored vascular access for hemodialysis of patients with chronic kidney disease(CKD) is an arteriovenous fistula (AVF).Failure of an AVF occurs mainly because of vascular stenosis which refl...
[会议论文] 作者：Jizhong Cheng,Yun Wang,Anlin Liang,Lixin Jia,Jie Du,
来源：第七届北京五洲心血管病研讨会 年份：2013
Objective To study how FSP—1 contributes to neointima formation of vein grafts.Methods Arteriovenous grafts were created in wild—type or FSP—1-GFP mice (green fluorescent protein expression regulated...
Macrophage-Stimulated Cardiac Fibroblast Production of IL-6 Is Essential for TGF β/Smad Activation a
[会议论文] 作者：Feifei Ma,Yulin Li,Lixin Jia,Yalei Han,Jizhong Cheng,Huihua Li,Yongfen Qi,Jie Du,
来源：第七届北京五洲心血管病研讨会 年份：2013
Interleukin6 (IL6) is an important cytokine participating in multiple biologic activities in immune regulation and inflammation.IL6 has been associated with cardiovascular remodeling.However,the mecha...
Cathepsin S Deficiency Results in Abnormal Accumulation of Autophagosomes in Macrophages and Enhance
[会议论文] 作者：Lili Pan,Yulin Li,Lixin Jia,Yanwen Qin,Guanming Qi,Jizhong Cheng,Yongfen Qi,Huihua Li,Jie Du,
来源：第七届北京五洲心血管病研讨会 年份：2013
Background Cathepsin S (Cat S) is overexpressed in human atherosclerotic and aneurysmal tissues and may contributes to degradation of extracellular matrix,especially elastin,in inflammatory diseases.W...
Interleukin-12p35 Deletion Promotes CD4 T-Cell-Dependent Macrophage Differentiation and Enhances Ang
[会议论文] 作者：Yulin Li,Jie Du,Congcong Zhang,Yina Wu,Yalei Han,Wei Cui,LixinJia,LunCai,Jizhong Cheng,Huihua Li,
来源：第八届北京五洲国际心血管病会议 年份：2014
Objective Interleukin-12 is essential for the differentiation of na(i)ve T cells into interferon-γ-producing T cells, which regulate inflammatory responses.We investigated this process of regulating h...
Proinflammatory Protein CARD9 Is Essential for Infiltration of Monocytic Fibroblast Precursors and C
[会议论文] 作者：Jingyuan Ren,Jie Du,Min Yang,Guanming Qi,Jiao Zheng,Lixin Jia,Jizhong Cheng,Cui Tian,Huihua Li,Xin Lin,
来源：第七届北京五洲心血管病研讨会 年份：2013
Background Angiotensin Ⅱ (Ang Ⅱ)-induced cardiac remodeling with the underlying mechanisms involving inflammation and fibrosis has been well documented.Cytosolic adaptor caspase recruitment domain 9 (...
Serum-Glucocorticoid Regulated Kinase 1 Regulates Alternatively Activated Macrophage Polarization Co
[会议论文] 作者：Min Yang,Huihua Li,Jizhong Cheng,Jie Du,Jiao Zheng,Yanjv Miao,Ying Wang,Wei Cui,Jun Guo,Shulan Qiu,Yalei,
来源：第七届北京五洲心血管病研讨会 年份：2013
Objective Inflammatory responses play a pivotal role in the pathogenesis of hypertensive cardiac remodeling.Macrophage recruitment and polarization contribute to the development of cardiac fibrosis.Al...
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