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[会议论文] 作者：Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
Antibiotics mediate warfare and signaling between organisms, but in most cases, the signaling mechanisms are not well understood.Here we show that exogenous ang...
[会议论文] 作者：Bin Wang,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
Kinamycins belong to atypical angucycline antibiotics synthesized by type Ⅱ polyketide synthases.Besides the diazo group of kinamycins which is rarely occurred...
[会议论文] 作者：Junjie Ji,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
Cephalosporins are widely used in the treatment of bacterial infections.A large proportion of clinically used cephalosporins are derived from 7-aminodeacetoxyce...
[会议论文] 作者：Chaobo Zhang,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
Spinosyns are unique type of macrolides produced by Saccharopolyspora spinosa composed of a tetracyclic macrolide covalently modified by tri-O-methyl rhamnose a...
CABE,AN EF-HAND CALCIUM-BINDING PROTEIN,IS INVOLVED IN MORPHOLOGICAL DEVELOPMENT IN STREPTOMYCES COE
[会议论文] 作者：Shenglan Wang,Keqian Yang,
来源：15th International Symposiium on the Biology of Actinomycete 年份：2009
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[会议论文] 作者：Yihong Li,Weishan Wang,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
Polyketides is a group of valuable secondary metabolites owing to their great importance in many fields such as medicine and agriculture.However, insufficient p...
[会议论文] 作者：Fang Guo,Sihai Xiang,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
A remarkable reservoir of natural product biosynthetic gene clusters has been uncovered along with the growing number of sequenced microbial genomes.However, ma...
[会议论文] 作者：Xiao Li,Weishan Wang,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
With the development of synthesis biology, widely used and well characterized regulatory elements are urgent needed.To develop a strong widely used promoter in...
[会议论文] 作者：Keqiang,Fan,Yihua Chen,Keqian Yang,
来源：15th International Symposiium on the Biology of Actinomycete 年份：2009
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[会议论文] 作者：Zhengzhong Zou,Weishan Wang,Keqian Yang,Huarong Tan,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
jadR3, encoding a deduced γ-butyrolactone receptor, is a barX homologue.Disruption of jadR3 greatly decreased the production of jadomycin and chloramphenicol.G...
Identification of key residues in JadH, an bifunctional monooxygenasedehydrase involved in jadomycin
[会议论文] 作者：Keqiang Fan,Xiaojing Peng,Guohui Pan,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
Jadomycin B, an atypical angucycline polyketide, is synthesized by Streptomyces venezuelae ISP5230 under stress conditions.JadH, a bifunctional post-PKS tailori...
[会议论文] 作者：Xiaozhou Feng,Weishan Wang,Keqian Yang,Xinli Liu,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
Spinosad represents a new class of insecticides produced by Saccharopolyspora spinosa.To understand the transcription of the spinosad biosynthetic gene cluster,...
[会议论文] 作者：Weishan Wang,Yue Li,Xiao Li,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
To construct a regulatory network, it is necessary to identify every transcription factors binding to a specific promoter.In this work, we developed a de nove d...
[会议论文] 作者：Guohui Pan,Xifen Zhu,Wubin Gao,Keqian Yang,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
Glycosylation is a common tailoring reaction in natural product biosynthesis.In most cases, the sugar moiety is necessary for exerting their biological activiti...
,Structural basis for prokaryotic calciummediated regulation by a Streptomyces coelicolor calcium bi
[期刊论文] 作者：Xiaoyan Zhao,Hai Pang,Shenglan Wang,Weihong Zhou,Keqian Yang,Mark Bartlam,
来源：蛋白质与细胞 年份：2010
The important and diverse regulatory roles of Ca2+ in eukaryotes are conveyed by the EF-hand containing calmodulin superfamily.However,the calcium-regulatory pr...
jadR negatively controls jadomycin production in Streptomyces venezuelae by regulating cluster-situa
[会议论文] 作者：Yanyan Zhang,Guohui Pan,Zhengzhong Zou,Linqi Wang,Keqian Yang,Huarong Tan,
来源：第一届中-欧放线菌生物学研讨会 年份：2013
jadR*, encoding a TetR family transcriptional regulator, situated in the jadomycin biosynthetic gene cluster of Streptomyces venezuelae ISP5230.Disruption of ja...
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