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Cryptopleurine Analogs with Modification of E Ring Exhibit Different Mechanism to Rac-cryptopleurine
[会议论文] 作者：Ying Wang,Kuo-Hsiung Lee,Yung-Chi Cheng,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
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Cryptopleurine Analogs with Modification of E Ring Exhibit Different Mechanism to Rac-cryptopleurine
[会议论文] 作者：Ying Wang,Kuo-Hsiung Lee,Yung-Chi Cheng,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
Tylophorine analogs exhibit a broad range of pharmacological activities, including anti-cancer, anti-inflammatory, anti-autoimmune, and anti-virus effects.Structure-activity relationship study of diff...
[会议论文] 作者：Li-Shian Shi,Kuo-Hsiung Lee,Tian-Shung Wu,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
An ethanol extract of the trunk bark of Antiaris toxicaria yielded five new flavanones,antiarins A-E(1-5),and two new coumarins,anticarins A and-B(6,7),in addition to four known coumarins.Their struct...
[会议论文] 作者：Zhiyan Xiao,Yu Zhao,Chung Y.Hsu,Kuo-Hsiung Lee,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
Stroke is the third most common cause of death.Only one drug, tissue plasminogen activator (TPA), has been approved by US FDA to treat stroke.More than 100 traditional Chinese Medicine (TCM), includin...
[期刊论文] 作者：Meng-ting CHANG,Jia-hua FENG,Kyoko NAKAGAWA-GOTO,Kuo-Hsiung LEE,Lie-Fen SHYUR,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE To investigate the pharmacological effect of a plant sesquiterpene lactone(designated D)and its semi-organically synthesized novel derivative(designat...
[期刊论文] 作者：谢百波,尚明英,王璇,蔡少青,Kuo-hsiung LEE,,
来源：药学学报 年份：2011
为了研究单叶细辛(Asarum himalaicum)的化学成分,利用溶剂提取、硅胶柱色谱、凝胶(SephadexLH-20)柱色谱和半制备型高效液相色谱(semi-preparative high performance liquid...
[会议论文] 作者：Jiadi Gao,Cheng Fang,Zhiyan Xiao,Li Huang,Chin-Ho Chen,Li-Ting Wang,Kuo-Hsiung Lee,
来源：第八届国际分子模拟与信息技术应用学术会议 年份：2016
Based on a 3D-QSAR pharmacophore derived from a diverse set of known cyclin-dependent kinase 9(CDK9)inhibitors and a composite pharmacophore extracted from the complex structure of flavopiridol(FVP)-C...
[会议论文] 作者：Mei-Juan Wang,Wen-Qun Li,Xiang Nan,Ying-Qian Liu,Keduo Qian,Guan-Fang Hu,Hai-Tao Yu,Kuo-Hsiung Lee,
来源：第十三届全国农药学教学科研研讨会 年份：2013
In an attempt to find the biorational pesticides, a series of novel acylthiourea derivatives of cantharidin (1) were designed, synthesized and evaluated for their bioactivity against T.Cinnabarinus an...
[会议论文] 作者：Mei-Juan Wang,Kuo-Hsiung Lee,Xiao-Bo Zhao,Masuo Goto,Susan L.,
来源：第十二届全国青年药学工作者最新科研成果交流会 年份：2014
Continuing our search for natural product-based spin-labeled antitumor drugs,a series of novel spin-labeled camptothecin derivatives were synthesized via a Cu-catalyzed one pot reaction and evaluated...
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