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Endosulfan induced cell cycle arrest and proliferation inhibition via the Notch signaling pathway in
[会议论文] 作者：Jialiu Wei,Lianshuang Zhang,Lihua Ren,Jin Zhang,Zhiwei Sun,Xianqing Zhou,
来源：第六届亚洲特大城市环境与公共健康论坛暨中国环境科学学会环境医学与健康分会2015年会 年份：2015
To investigate the molecular mechanism of endosulfan damaging endothelial cell, human umbilical vein endothelial cells (HUVECs) were exposed to 1,6, 12 μg/...
Silica nanoparticles induce abnormal mitosis and apoptosis by balance and regulation of PKC mediated
[会议论文] 作者：Jin Zhang,Lihua Ren,Lianshuang Zhang,Jialiu Wei,Liu jianhui,Zhiwei Sun,Xianqing Zhou,
来源：第六届中国毒理学会免疫毒理专业委员会换届及学术会议 年份：2016
Researches had shown that SiNPs could damage seminiferous epithelium and reduce the quantity and quality of sperms, but little is known about the toxicity mechanism of SiNPs on male reproductive syste...
Silica nanoparticles induce the apoptosis and necroptosis of spermatogenic cells by RIPK1 signal pat
[会议论文] 作者：Lihua Ren,Jin Zhang,Yang Zou,Lianshuang Zhang,Jialiu Wei,Zhiwei Sun,Xianqing Zhou,
来源：第十一届全国野生动物生态及自然资源学术研讨会 年份：2015
Although it is known that nanoparticles is of reproductive toxicity,it is not clear about its mechanism.To investigate the toxicity mechanism of silica nanoparticles(SiNPs)on spermatogenic cells,sixty...
Endosulfan inducing the apoptosis by activating the negative regulation pathway of cell cycle and de
[会议论文] 作者：Fang-Zi Guo,Ying Xu,Lihua Ren,Jin Zhang,Li Jing,Man Yang,Ji Wang,Zhi-Wei Sun,Xian-Qing Zhou,
来源：2016(第二届)毒性测试替代方法与转化毒理学(国际)学术研讨会暨有害结局路径(AOP)与风险评估培训会议 年份：2016
The male reproductive toxicity of endosulfan has been proved.However, the molecular mechanisms underlying the apoptosis effects of endosulfan in spermatogenic cells remain poorly understood.To investi...
Silica nanopaticles induce male reproductive toxicity by inhibiting the start and process of meiosis
[会议论文] 作者：Jin Zhang,Lihua Ren,Yang Zou,Lianshuang Zhang,Jialiu Wei,Yanbo Li,Ji Wang,Zhiwei Sun,Xianqing Zhou,
来源：2016(第二届)毒性测试替代方法与转化毒理学(国际)学术研讨会暨有害结局路径(AOP)与风险评估培训会议 年份：2016
Silica nanoparticles induced reproductive toxicity, but its mechanism is unknown.To investigate toxic mechanism of SiNPs, 60 male mice were randomly divided into three groups:control group, saline gro...
Endosulfan induced cell cycle arrest via the Notch signaling pathway and damaging the cytoskeleton i
[会议论文] 作者：Jialiu Wei,Lianshuang Zhang,Lihua Ren,Jin Zhang,Yang Yu,Ji Wang,Junchao Duan,Zhiwei Sun,Xianqing Zhou,
来源：2016(第二届)毒性测试替代方法与转化毒理学(国际)学术研讨会暨有害结局路径(AOP)与风险评估培训会议 年份：2016
Our previous study showed that endosulfan could trigger the extrinsic coagulation pathway via damaging endothelial cells and cause the hypercoagulability of blood.To investigate the mechanism of endos...
Silica nanoparticles induce start inhibition of meiosis and cell cycle arrest via down-regulating me
[会议论文] 作者：Jin Zhang,Lihua Ren,Yang Zou,Lianshuang Zhang,Jialiu Wei,Yanbo Li,Ji Wang,Zhiwei Sun,Xianqing Zhou,
来源：首都医科大学第四届研究生学术论坛第二分论坛 年份：2016
Silica nanoparticles have been shown to induce reproductive toxicity,but the mechanism is unknown.To investigate toxic mechanism of SiNPs,60 male mice were randomly divided into three groups:control g...
Fine particulate matters inducing reproductive impairment by causing cell cycle arrest and activatin
[会议论文] 作者：Jianhui Liu,Lihua Ren,Jialiu Wei,Jin Zhang,Yannan Zhang,Hejing Hu,Junchao Duan,Zhiwei Sun,Xianqing Zhou,
来源：中国环境诱变剂学会第七届全国会员代表大会暨第十七次学术大会 年份：2017
Fine particulate matters(PM2.5)have been associated with male reproductive toxicity,but the underlying mechanism is unclear.To explore the effect of PM2.5,32 male Sprague-Dawley(SD)rats were treated t...
Endosulfan inhibited the start and process of meiosis via depression of Sohlh1 expression and G2M ph
[会议论文] 作者：FangZi Guo,LianShuang Zhang,JiaLiu Wei,LiHua Ren,Jin Zhang,Li Jing,Man Yang,Ji Wang,ZhiWei Sun,XianQing,
来源：第六届亚洲特大城市环境与公共健康论坛暨中国环境科学学会环境医学与健康分会2015年会 年份：2015
Abstract : Endosulfan is a persistent organic pollutant and widely used in agriculture as a pesticide.To investigate the effect of endosulfan on meiosis pro...
Silica Nanoparticles Induce the Apoptosis and Necroptosis of Spermatogenic Cells by RIPK1 Signal Pat
[会议论文] 作者：Lihua Ren,Jin Zhang,Yang Zou,Lianshuang Zhang,Jialiu Wei,Zhiwei Sun,Zhixiong Shi,Caixia Guo Yanbo Li,,
来源：首都医科大学第三届研究生学术论坛 年份：2015
Although it is known that nanoparticles is of reproductive toxicity, it is not clear about its mechanism.To investigate the toxicity mechanism of silica nanoparticles (SiNPs) on spermatogenic cells, s...
Silica nanoparticles exposure inducing granulosa cell apoptosis and follicular atresia in female Bal
[会议论文] 作者：Jianhui Liu,Man Yang,Li Jing,Lihua Ren,Jialiu Wei,Jin Zhang,Feng Zhang,Junchao Duan,Xianqing Zhou,Zhiwei,
来源：中国环境诱变剂学会第七届全国会员代表大会暨第十七次学术大会 年份：2017
Given that the effects of ultrafine fractions(...
Endosulfan inhibited the start and process of meiosis via depression of Sohlh1 expression and G2/M p
[会议论文] 作者：Fangzi Guo,Lianshuang Zhang,Jialiu Wei,Lihua Ren,Jin Zhang,Li Jing,Man Yang,Ji Wang,Zhiwei Sun,Xianqing,
来源：第十一届全国野生动物生态及自然资源学术研讨会 年份：2015
Endosulfan is a persistent organic pollutant and widely used in agriculture as a pesticide.To investigate the effect of endosulfan on meiosis process,32 rats were divided into 4 groups,treated with 0,...
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