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Natural product compound 3c ameliorates brain inflammation and brain ischemic stroke via AMPK-mediat
[会议论文] 作者：Yun-Jie Wang,Wen-Chen Ruan,Lu-Yong Zhang,Tao Pang,
来源：2016年国际生理学学术大会 年份：2016
Brain inflammation plays an important role in the pathophysiology of brain ischemic stroke,psychiatric and neurological diseases.During brain inflammation,microglia cells are activated and show pro-in...
[会议论文] 作者：Wei-gang DUAN,Lu-yong ZHANG,Jin KE,Xiao-man LV,Hua YIN,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: The main aim is to observe the changes in major pharmacological effect and safety of Chinese Meteria Medica injection (CMMI) when the macromolecular substances in them are removed.Methods: Two ki...
[期刊论文] 作者：Xin-zhi Wang,Ru-feng Xue,Shen-ye Zhang,Ya-ting Zheng,Lu-yong Zhang,Zhen-zhou Jiang,
来源：中国药理学报（英文版） 年份：2018
Triptolide (TP) is the main active ingredient of Tripterygium wilfordii Hook.f,which has attracted great interest due to its promising efficacy for autoimmune d...
,Telmisartan protects central neurons against nutrient deprivation-induced apoptosis in vitro throug
[期刊论文] 作者：Tao PANG,Li-xin SUN,Tao WANG,Zhen-zhou JIANG,Hong LIAO,Lu-yong ZHANG,
来源：中国药理学报（英文版） 年份：2014
...
,Triptolide inhibits human breast cancer MCF-7 cell growth via downregulation of the ERα-mediated si
[期刊论文] 作者：Han LI,Guo-feng PAN,Zhen-zhou JIANG,Jing YANG,Li-xin SUN,Lu-yong ZHANG,
来源：中国药理学报（英文版） 年份：2015
...
Ristimerin inhibits Colorectal Cancer cells Growth through Induction of G1-phase Cell Cycle Arrest a
[会议论文] 作者：Bashir A.Yousef,Mounia Guerram,Hozeifa M.Hassan,Aida M.Hamdi,Lu-Yong Zhang,Zhen-Zhou Jiang,
来源：2015医学前沿论坛暨第十四届全国肿瘤药理与化疗学术会议 年份：2015
Pristimerin is a naturally occurring triterpenoid that causes cytotoxicity in several cancer cell lines.However, the cytotoxic effects of pristimerin as well as its molecular mechanisms of action agai...
[会议论文] 作者：Tao Pang,Yuan Xu,Ya-Zhou Xu,Yun-Jie Wang,Hong Liao,Lu-Yong Zhang,
来源：The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份：2015
Objective Brain inflammation plays an important role in the pathophysiology of many psychiatric and neurological diseases.Angiotensin II type 1 receptor blockers(ARBs)ameliorate brain inflammation and...
,The natural product 4,10-aromadendranediol induces neuritogenesis in neuronal cells in vitro throug
[期刊论文] 作者：Sai CHANG,Wen-chen RUAN,Ya-zhou XU,Yun-jie WANG,Jie PANG,Lu-yong ZHANG,Hong LIAO,
来源：中国药理学报（英文版） 年份：2017
...
[期刊论文] 作者：Fang-hua HUANG,Xin-yue ZHANG,Lu-yong ZHANG,Qin LI,Bin NI,Xiao-liang ZHENG,Ai-jun CHEN,
来源：中国药理学报（英文版） 年份：2010
...
,Topotecan inhibits cancer cell migration by down-regulation of chemokine CC motif receptor 7 and ma
[期刊论文] 作者：Sen-sen LIN,Li SUN,Yan-kai ZHANG,Ren-ping ZHAO,Wen-lu LIANG,Sheng-tao YUAN,Lu-yong ZHANG,
来源：中国药理学报（英文版） 年份：2009
Aim: The aim of this study was to investigate the effect of topotecan (TPT) on cancer cell migration.Methods: Growth inhibition of TPT was analyzed by MTT assay...
Tripterygium wilfordii multiglycoside-induced hepatotoxicity via inflammation and apoptosis in zebra
[期刊论文] 作者：DUAN Xiu-Ying,MA Rui-Jiao,HSIAO Chung-Der,JIANG Zhen-Zhou,ZHANG Lu-Yong,ZHANG Yun,LIU Ke-Chun,
来源：中国天然药物 年份：2021
Tripterygium wilfordii multiglycoside(GTW)is a commonly used compound for the treatment of rheumatoid arthritis(RA)and immune diseases in clinical practice.However,it can induce liver injury and the mechanism of hepatotoxicity is still not ......
,WIN55,212-2 protects oligodendrocyte precursor cells in stroke penumbra following permanent focal c
[期刊论文] 作者：Jing SUN,Yin-quan FANG,Hong REN,Tao CHEN,Jing-jing GUO,Jun YAN,Shu SONG,Lu-yong ZHANG,Hong LIAO,
来源：中国药理学报（英文版） 年份：2013
...
Catalpol counteracts the pathology in a mouse model of Duchenne muscular dystrophy by inhibiting the
[期刊论文] 作者：Deng-qiu Xu,Lei Zhao,Si-jia Li,Xiao-fei Huang,Chun-jie Li,Li-xin Sun,Xi-hua Li,Lu-yong Zhang,Zhen-zhou,
来源：中国药理学报：英文版 年份：2021
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease caused by a mutation in the gene encoding the dystrophin protein. Catalpol is an iridoid glycoside found in Chinese herbs with anti-inflammatory, anti-oxidant, anti-ap......
[期刊论文] 作者：Deng-qiu Xu,Chun-jie Li,Zhen-zhou Jiang,Lu Wang,Hong-fei Huang,Zhi-jian Li,Li-xin Sun,Si-si Fan,Lu-yong Zhang,
来源：中国药理学报（英文版） 年份：2020
Mitochondria serve as sensors of energy regulation and glucose levels,which are impaired by diabetes progression.Catalpol is an iridoid glycoside that exerts a...
The potential utility of acetyltanshinone Ⅱ A in the treatment of HER-2-overexpressed breast cancer:
[会议论文] 作者：Bashir Alsiddig Yousef,Aida Mejda Hamdi,Hozeifa Mohamed Hassan,Zi-Qiao Yuan,Hou-Wei Luo,Xiong Zhu,Lu-Yong Zhang,
来源：2015医学前沿论坛暨第十四届全国肿瘤药理与化疗学术会议 年份：2015
Aim HER-2 is an important oncoprotein which overexpression, found in more than 30% of breast cancers, is strongly associated with aggressiveness, chemoresistance, and poor prognosis.The purpose of the...
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