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[会议论文] 作者：Luonan Chen,
来源：第一届国际转化医学信息学会议 年份：2012
Considerable evidence suggests that during the progression of complex diseases, the deteriorations are not necessarily smooth but are abrupt, and may cause...
[会议论文] 作者：Luonan Chen,
来源：The International Conference on Computational and Systems Bi 年份：2011
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[会议论文] 作者：Luonan Chen,
来源：第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 年份：2014
Considerable evidence suggests that during the progression of complex diseases, the deteriorations are not necessarily smooth but are abrupt, and may cause...
Diagnosing Un-occurred Diseases with Single Sample by Dynamic Network Biomarkers-Detecting the tippi
[会议论文] 作者：Luonan Chen,
来源：第二届中国计算机学会生物信息学会议 年份：2017
Considerable evidence suggests that during the progression of complex diseases,the deteriorations are not necessarily smooth but are abrupt,and may cause a...
[期刊论文] 作者：Zhi-Ping Liu,Luonan Chen,
来源：蛋白质与细胞 年份：2012
In this paper,we present a brief review of the existing computational methods for predicting proteome-wide protein-protein interaction networks from highthr...
[期刊论文] 作者：Peng Wang,Luonan Chen,
来源：定量生物学（英文版） 年份：2020
Background: Phase transition and phase separation as well as their tipping points are penetrating phenomena in biology and are intrinsic properties of biologica...
[期刊论文] 作者：Yixue Li,Luonan Chen,
来源：黑龙江科技信息 年份：2014
本文通过对荣华二采区10...
[期刊论文] 作者：Luonan CHEN,Xiang-Sun ZHANG,
来源：系统科学与复杂性学报（英文版） 年份：2010
Systems Biology has been greatly boomed recently and attracted many leading scientists in Biology, Physics, Mathematics, Computer Science, Optimization, and St...
[会议论文] 作者：Luonan Chen,Ruiqi Wang,Kazuyuki Aihara,
来源：The International Conference on Computational and System Bio 年份：2009
...
,Dynamical network biomarkers for identifying critical transitions and their driving networks of bio
[期刊论文] 作者：Rui Liu,Kazuyuki Aihara,Luonan Chen,
来源：定量生物学（英文版） 年份：2013
...
[期刊论文] 作者：Jifan Shi,Kazuyuki Aihara,Luonan Chen,
来源：国家科学评论（英文版） 年份：2021
Life science has long been a rich subject for research, and continues to develop at high speed.One of the major aims of life science is to study the mechanisms...
Advanced Single-cell Omics Technologies and Informatics Tools for Genomics, Proteomics, and Bioinfor
[期刊论文] 作者：Luonan Chen,Rong Fan,Fuchou Tang,
来源：基因组蛋白质组与生物信息学报（英文版） 年份：2021
The newly developed technologies for profiling cellular heterogeneity have spurred a world-wide pursuit of single-cell analysis in the field of omics studies, investigating the genome, epigenome, transcriptome, proteome, metabo-lome, and th......
[期刊论文] 作者：Zhenping LI,Ruisheng WANG,Xiang-Sun ZHANG,Luonan CHEN,
来源：系统科学与复杂性学报（英文版） 年份：2010
Detecting communities from complex networks is an important issue and has attracted attention of researchers in many fields. It is relevant to social tasks, bio...
[期刊论文] 作者：Lin Li,Hao Dai,Zhaoyuan Fang,Luonan Chen,
来源：基因组蛋白质组与生物信息学报（英文版） 年份：2021
The rapid advancement of single-cell technologies has shed new light on the complex mechanisms of cellular heterogeneity.However,compared to bulk RNA sequencing (RNA-seq),single-cell RNA-seq (scRNA-seq) suffers from higher noise and lower c......
[期刊论文] 作者：Jiang Xie,Zhonghua Zhou,Kai Lu,Luonan Chen,Wu Zhang,,
来源：Tsinghua Science and Technology 年份：2013
Similarities and dissimilarities between biomolecular networks cannot be intuitively recognized even after the development of several comparison algorithms because of the lack of visualization tools....
[期刊论文] 作者：Dengyu LIU,Xiao CHANG,Zengrong LIU,Luonan CHEN,Ruiqi WANG,
来源：系统科学与复杂性学报（英文版） 年份：2010
Many interacting biomolecular components in cells form different positive or negative feedback loops. When biological signals transduce through cascades consist...
Preliminary analysis of inflammatory mediator network for prognosis in non-small cell lung cancer (N
[会议论文] 作者：Tao Zeng,Dawei Yang,Xiangdong Wang,Chunxue Bai,Luonan Chen,
来源：第五届全国生物信息学与系统生物学学术大会 年份：2012
Background: Inflammation plays an important role in lung cancer development and cancer therapy.To identify potential protein markers for prognosis in non-small cell lung cancer (NSCLC) patients receiv...
[期刊论文] 作者：Xiaoping Liu,Xiao Chang,Siyang Leng,Hui Tang,Kazuyuki Aihara,Luonan Chen,
来源：国家科学评论（英文版） 年份：2019
A new model-free method has been developed and termed the landscape dynamic network biomarker (l-DNB) methodology. The method is based on bifurcation theory, wh...
Kinase–substrate Edge Biomarkers Provide A More Accurate Prognostic Prediction in ER-negative Breast
[期刊论文] 作者：Yidi Sun,Chen Li,Shichao Pang,Qianlan Yao,Luonan Chen,Yixue Li,Rong Zeng,
来源：基因组蛋白质组与生物信息学报（英文版） 年份：2004
The estrogen receptor (ER)-negative breast cancer subtype is aggressive with few treat-ment options available. To identify specific prognostic factors for ER-ne...
Predicting local COVID-19 outbreaks and infectious disease epidemics based on landscape network entr
[期刊论文] 作者：Rui Liu,Jiayuan Zhong,Renhao Hong,Ely Chen,Kazuyuki Aihara,Pei Chen,Luonan Chen,
来源：科学通报（英文版） 年份：2021
As a highly infectious disease,the reproduction number of coro-navirus disease 2019 (COVID-19) was estimated to be as high as 6.47 in the early stage [1].Many studies have suggested that early interventions,such as the use of masks,social d......
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