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Systematic drug discovery and therapeutic target identification by in silico virtual screening in Tr
[会议论文] 作者：Mingzhu Zhao,
来源：The International Conference on Computational and Systems Bi 年份：2011
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Systematic drug discovery and therapeutic target identification by in silico virtual screening in Tr
[会议论文] 作者：Mingzhu Zhao,
来源：The International Conference on Computational and Systems Bi 年份：2011
...
[期刊论文] 作者：Mingzhu Zhao,Tao Liu,
来源：运动科学：英文版 年份：2016
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[期刊论文] 作者：Mingzhu Zhao,Zuobin Ma,Lili Wa,
来源：作物学报:英文版 年份：2020
Panicle traits directly associated with yield are a target of selection in rice breeding.Although abundant QTL for panicle traits have been identified,there is...
Clinical implications and prognostic value of single and combined biomarkers in endometrial carcinom
[期刊论文] 作者：Li Mingzhu,Zhao Lijun,Shen Dan,
来源：中华医学杂志（英文版） 年份：2014
Background Endometrial carcinoma is one of the most common gynecological cancers and the incidence has been increasing.This study was to identify the relationsh...
[期刊论文] 作者：Quan Xu,Mingzhu Zhao,Kun Wu,Xi,
来源：黑龙江科技学院学报 年份：2016
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7...
Clinical implications and prognostic value of single and combined biomarkers in endometrial carcinom
[期刊论文] 作者：Li Mingzhu,Zhao Lijun,Shen Danhua,Li Xiaoping,Wang Jianliu,Wei Lihui,
来源：中华医学杂志英文版 年份：2014
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Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators
[期刊论文] 作者：Shaoyong Lu,Yingyi Chen,Jiacheng Wei,Mingzhu Zhao,Duan Ni,Xinheng He,Jian Zhang,
来源：药学学报（英文版） 年份：2021
The recent discovery of activator compounds binding to an allosteric site on the NAD+-dependent protein lysine deacetylase,sirtuin 6(SIRT6)has attracted interest and presents a pharmaceu-tical target for aging-related and cancer diseases.Ho......
[期刊论文] 作者：Mingzhu Zhao,Zuobin Ma,Lili Wang,Zhiqiang Tang,Ting Mao,Chuanbin Liang,Hong Gao,Liying Zhang,Na He,Liang,
来源：作物学报（英文版） 年份：2020
Panicle traits directly associated with yield are a target of selection in rice breeding. Although abundant QTL for panicle traits have been identified, there i...
Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migrati
[期刊论文] 作者：Chen,Duan Ni,Zhimin Huang,Jiacheng Wei,Li Feng,Jun-Cheng Su,Yingqing Wei,Shaobo Ning,Xiuyan Yang,Mingzhu Zhao,
来源：药学学报（英文版） 年份：2022
SIRT6 belongs to the conserved NAD+-dependent deacetylase superfamily and mediates multiple biological and pathological processes.Targeting SIRT6 by allosteric modulators represents a novel direction for therapeutics,which can overcome the ......
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