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TNF-α impairs EP4 signaling through the association of TRAF2-GRK2 in primary fibroblast-like synovio
[期刊论文] 作者：Yu Tai,Bei Huang,Pai-pai Guo,Zhen Wang,Zheng-wei Zhou,Man-man Wang,Han-fei Sun,Yong Hu,Sheng-lin Xu,Ling-ling,
来源：中国药理学报（英文版） 年份：2022
Our previous study showed that chronic treatment with tumor necrosis factor-α(TNF-α)decreased cAMP concentration in fibroblast-like synoviocytes(FLSs)of collagen-induced arthritis(CIA)rats.In this study we investigated how TNF-α impairs ......
[期刊论文] 作者：Wei-jie Zhou,Dan-dan Wang,Juan Tao,Yu Tai,Zheng-wei Zhou,Zhen Wang,Pai-pai Guo,Wu-yi Sun,Jing-yu Chen,
来源：中国药理学报（英文版） 年份：2021
β-arrestin2 (β-arr2) is,a key protein that mediates desensitization and internalization of G protein-coupled receptors and participates in inflammatory and im...
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