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Combined inhibition of HDAC and DNMT1 induces p85α/MEK-mediated cell cycle arrest by dual target inh
[期刊论文] 作者：Yue Ren,Qinsheng Sun,Zigao Yua,
来源：黑龙江科技学院学报 年份：2019
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7...
Synthesis of gold nanoparticles bearing modified tumor-associated carbohydrate antigens as potential
[会议论文] 作者：Zhao Lei,Qinsheng Sun,Chunyan Tan,Yuyang Jiang,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
The aberrant carbohydrate structure expressing on the surface of cancer cells known as tumor-associated carbohydrate antigens(TACAs),provide a target for cancer vaccines....
Design, synthesis and biological evaluation of novel phthalazinone acridine derivatives as dual PARP
[期刊论文] 作者：Qiuzi Dai,Jiwei Chen,Chunmei Gao,Qinsheng Sun,Zigao Yuan,Yuyang Jiang,
来源：中国化学快报（英文版） 年份：2020
In this study, we designed and synthesized a series of phthalazinone acridine derivatives as dual PARP and Topo inhibitors. MTT assays indicated that most of th...
Design,synthesis and antitumor evaluations of nucleoside base hydroxamic acid derivatives as DNMT an
[期刊论文] 作者：Qinsheng Sun,Qiuzi Dai,Cunlong Zhang,Yan Chen,Lei Zhao,Zigao Yuan,Yuyang Jiang,
来源：中国化学快报（英文版） 年份：2021
DNA methyltransferase (DNMT) and histone deacetylase (HDAC) are well recognized epigenetic targets for discovery of antitumor agents.In this study,we designed and synthesized a series of nucleoside base hydroxamic acid derivatives as DNMT a......
Phytoplankton pigment pattern in the subsurface chlorophyll maximum in the South Java coastal upwell
[期刊论文] 作者：GAO Chunlei,FU Mingzhu,SONG Hongjun,WANG Lei,WEI Qinsheng,SUN Ping,LIU Lin,ZHANG Xuelei,
来源：黑龙江科技信息 年份：2018
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