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Tryptophan 2,3-dioxygenase 2 controls M2 macrophages polarization to promote esophageal squamous cel
[期刊论文] 作者:Yumiao Zhao,Jiaxin Sun,Yin Li,Xiuman Zhou,Wenjie Zhai,Yahong Wu,Guanyu Chen,Shanshan Gou,Xinghua Sui,,
来源:药学学报(英文版) 年份:2021
Tryptophan 2,3-dioxygnease 2(TDO2)is specific for metabolizing tryptophan to kynurenine(KYN),which plays a critical role in mediating immune escape of cancer.Although accumulating evidence demonstrates that TDO2 overexpression is implicated......
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