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[会议论文] 作者：Xiangkun Han,Fuming Li,Zhaoyuan Fang,Yijun Gao,Shun Yao,Li Li,Hongbin Ji,Yingyong Hou,
来源：中国细胞生物学学会2013年全国学术大会 年份：2013
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[会议论文] 作者：Xiangkun Han,Fuming Li,Zhaoyuan Fang,Yijun Gao,Shun Yao,Li Li,Yingyong Hou,Hongbin Ji,
来源：中国细胞生物学学会2013年全国学术大会 年份：2013
Lineage transition in different subtypes of non-small cell lung cancer (NSCLC),as implicated by clinical observation of mixed adenocarcinoma (ADC) and squamous cell carcinoma (SCC) pathologies in aden...
Lysyl oxidase inhibition drives the transdifferentiation from lung adenocarcinoma to squamous cell c
[会议论文] 作者：yueqing Chen,Shun Yao,Xiangkun Han,Xinyuan Tong,Fuming Li,Zhen Qin,Hsin-yi Huang,Hongbin Ji,
来源：2019中国肿瘤学大会 年份：2019
Objective Lkb1 deficiency is the only well-established factor in driving lung adenocarcinoma(ADC)to squamous cell carcinoma(SCC)transdifferentiation(AST)in mice.AST has been reported to correlate with...
[期刊论文] 作者：Yuetong Wang,Zhaoyuan Fang,Hua Wang,Jian Zhang,Longfu Zhang,Hsinyi Huang,Zhonglin Jiang,Yujuan Jin,Xiangkun Han,
来源：国家科学评论（英文版） 年份：2021
Somatic mutations of the chromatin remodeling gene ARID2 are observed in ～7% of human lung adenocarcinomas (LUADs). However, the role of ARID2 in the pathogenesis of LUADs remains largely unknown. Here we find that ARID2 expression is decrea......
YAP functions as an essential barrier for squamous transdifferentiation of Lkb1-deficient lung adeno
[会议论文] 作者：Zhaoyuan Fang,Lei Zhang,Fuming Li,Yan Feng,Yijun Gao,Xingyuan Tong,Hongbin Ji,Xiangkun Han,Fei Li,Wenjing,
来源：中国细胞生物学学会2015年全国学术大会 年份：2015
Whether the Hippo pathway contributes to cell lineage transition under pathological conditions, especially tumorigenesis, remains largely unknown....
YAP functions as an essential barrier for squamous transdifferentiation of Lkb1-deficient lung adeno
[会议论文] 作者：Yijun Gao,Wenjing Zhang,Xiangkun Han,Fuming Li,Xujun Wang,Rui Wang,Zhaoyuan Fang,Xingyuan Tong,Shun Yao,
来源：中国细胞生物学学会2015年全国学术大会 年份：2015
Whether the Hippo pathway contributes to cell lineage transition under pathological conditions, especially tumorigenesis, remains largely unknown....
[期刊论文] 作者：Fuming Li,Xiangkun Han,Fei Li,Rui Wang,Hui Wang,Yijun Gao,Xujun Wang,Zhaoyuan Fang,Wenjing Zhang,Shun,
来源：科学新闻 年份：2016
文章简介临床上肺腺鳞癌的存在提示肺腺癌和肺鳞癌之间可能存在着谱系转化。课题组前期工作发现LKB1缺失会导致小鼠肺腺癌向肺鳞癌发生转分化,从而证实了该临床假说,但其...
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