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Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability
[会议论文] 作者：Xiao-Na DU,Chao WANG,Hai-Lin ZHANG,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Nociceptive responses to noxious stimuli are initiated at peripheral nociceptor terminals.Ion channels play a vital role in pain signal initiation and conduction.Activation of KATP channels has been i...
[期刊论文] 作者：Chuan WANG,Xiao-na DU,Qing-zhong JIA,Hai-lin ZHANG,
来源：中国药理学报(英文版) 年份：2005
Aim: To investigate the effects of the pleckstrin homology (PH) domain of phospholipase Cδ1 (PLCδ1PH) on inhibition of phospholipase C (PLC)-mediated hydrolys...
[会议论文] 作者：Cai-xue Wang,Han Hao,Yi Li,Yong-Xue Zhang,Hai-Lin Zhang,Xiao-na Du,
来源：The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份：2015
Objective: Evaluating change and effect of GABA system in neuropathic pain.Methods: CCI model of rats; Radiate heat and Von Frey filament test; DRG targeted mini-pump implantation; Whole cell patch cl...
[会议论文] 作者：Fan ZHANG,Jing-Jing MA,Yi MI,Jin-Long QI,Qing-Zhong JIA,Xiao-Na DU,Hai-Lin ZHANG,
来源：The 3rd Ion Channel Conference: Ion channels-Structure, Func 年份：2011
Voltage-gated Kv7/KCNQ/M-potassium channels play an essential role in setting the resting membrane potential and in controlling the excitability of neurons.Mutation or depression of KCNQ channels resu...
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