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[期刊论文] 作者：YUAN Hai-long,ZHANG Tian-tian,,
来源：中草药 年份：2011
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7...
Mixed nanomicelles loaded with thymopeptides-sodium deoxycholate/phospholipid improve drug absorptio
[期刊论文] 作者：JIN Shi-Xiao,JIN Shi-Ying,LV Qing-Yuan,FU Shan-Shan,HAN Jin,YUAN Hai-Long,,
来源：Chinese Journal of Natural Medicines 年份：2014
AIM: To improve the absorption of thymopeptides(TH) by preparing sodium deoxycholate/phospholipid-mixed nanomicelles(SDC/PL-MMs). METHODS: TH-SDC/PL-MMs were pr...
Comparison of anti-bacterial activity of three types of di-O-caffeoylquinic acids in Lonicera japoni
[期刊论文] 作者：HAN Jin,LV Qing-Yuan,JIN Shi-Ying,ZHANG Tian-Tian,JIN Shi-Xiao,LI Xian-Yi,YUAN Hai-Long,,
来源：Chinese Journal of Natural Medicines 年份：2014
The anti-bacterial activities of three types of di-O-caffeoylquinic acids(diCQAs) in Lonicera japonica flowers, a traditional Chinese medicine(TCM), on Bacillus...
Research on the Daily Administration Times of Composite Yinchen tablet in Iceteric Rats Based on PD/
[会议论文] 作者：LV Jun-lan,JIN Shi-ying,YUAN Hai-long,XIAO Xiao-he,FU Shan-shan,JIN Shi-xiao,GUO Jing-jing,
来源：2011年中国药学大会暨第11届中国药师周 年份：2011
To study the rational daily administration times of Composite Yinchen tablet(CYT) when it is used to treat experimental jaundice in rats based on PD/PK model. Methods: Rats were modeled by 4％ ANIT(75m...
Improved stability and oral bioavailability of Ganneng dropping pills following transforming lignans
[期刊论文] 作者：LI Juan-Juan,CHENG Ling,SHEN Gang,QIU Ling,SHEN Cheng-Ying,ZHENG Juan,XU Rong,YUAN Hai-Long,
来源：中国天然药物 年份：2018
The present study was designed to improve storage stability and oral bioavailability of Ganneng dropping pills (GNDP)by transforming lignans of Herpetospermum caudigerum (HL) composed of herpetrione (HPE) and herpetin (HPN) into nanosuspens......
Changes of Pharmacokinetics of 6,7-Dimethoxycoumarin in A Rat Model of Alpha-Naphthylisothiocyanate-
[期刊论文] 作者：LV Jun-lan,LI Rui-sheng,JIN Shi-ying,YUAN Hai-long,FU Shan-shan,HAN Jin,JIN Shi-xiao,XIAO Xiao-he,
来源：中国结合医学杂志（英文版） 年份：2012
...
Characterization and evaluation in vivo of baicalin-nanocrystals prepared by an ultrasonic-homogeniz
[期刊论文] 作者：JIN Shi-Ying,HAN Jin,JIN Shi-Xiao,LV Qing-Yuan,BAI Jin-Xia,CHEN Hong-Ge,LI Rui-Sheng,WU Wei,YUAN Hai-Long,
来源：Chinese Journal of Natural Medicines 年份：2014
AIM: To improve the absorption and bioavailability of baicalin using a nanocrystal(or nanosuspension) drug delivery system. METHODS: A tandem, ultrasonic-homoge...
[期刊论文] 作者：SHEN Cheng-Ying,DAI Ling,SHEN Bao-De,ZHOU Xu,BAI Jin-Xia,XU He,LV Qing-Yuan,HAN Jin,YUAN Hai-Long,,
来源：Chinese Journal of Natural Medicines 年份：2015
The objective of this study was to prepare nanostructured lipid carrier(NLC)-based topical gel of Ganoderma Triterpenoids(GTs) and evaluate their effects on fro...
[会议论文] 作者：JIN Shi-ying,靳世英,YUAN Hai-long,袁海龙,JIN Shi-xiao,靳士晓,HAN Jin,韩晋,
来源：2012转化医学与中药现代化高峰论坛 年份：2012
目的：本研究制备了黄芩苷纳米晶体(BC-NC),并进行了大鼠体内药物动力学研究.方法：采用探头超声结合高压均质法制备黄芩苷纳米混悬剂,然后通过流化干燥工艺将其脱水干燥成固体微丸,考察纳米晶体的形态、粒径分布及Zeta电位.以黄芩苷为指标成分,采用HPLC测定大鼠灌......
Formulation of dried lignans nanosuspension with high redispersibility to enhance stability,dissolut
[期刊论文] 作者：CHENG Ling,WANG Li-Qiang,ZHANG Li-Hong,SHEN Bao-De,LIAO Wei-Bo,LI Juan-Juan,ZHENG Juan,XU Rong,YUAN Hai-Long,
来源：Chinese Journal of Natural Medicines 年份：2016
Herpetospermum caudigerum lignans(HTL), one of the potential drugs with anti-hepatitis B virus and hepatoprotective effects, has limited clinical applications b...
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