Cardiomyocytes相关论文
Establishment of an in vitro safety assessment model for lipid-lowering drugs using same-origin huma
Cardiovascular safety assessment is vital for drug development,yet human cardiovascular cell models are lacking.In vitro......
Berberine Inhibits Norepinephrine-Induced Apoptosis in Neonatal Rat Cardiomyocytes via Inhibiting RO
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Apelin-APJ Effects of Ginsenoside-Rb1 Depending on Hypoxia-Induced Factor 1α in Hypoxia Neonatal Car
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Ginsenoside Rb1 Ameliorates Autophagy of Hypoxia Cardiomyocytes from Neonatal Rats via AMP-Activated
Objective:To investigate whether ginsenoside-Rb1 (Gs-Rb1) improves the CoCl2-induced autophagy of cardiomyocytes via upr......
Bufalin is one of the main pharmacological and toxicological components of Venenum Bufonis and many traditional Chinese ......
The calcium-activated chloride channels (CaCCs) are critical for many physiolo-gical functions.In cardiac tissues, CaCCs......
Assessing the roles of cardiac INa and ITo currents in the cellular mechanism of the Brugada syndrom
Background: Brugada syndrome(BrS)is an inherited cardiac condition characterized by signature changes in the electrocard......
The H2S Donor NaHS Changes the Expression Pattern of H2S-Producing Enzymes after Myocardial Infarcti
Aims: To examine the expression patterns of hydrogen sulphide-(H2S-)producing enzymes in ischaemic heart tissue and plas......
AMP-activated protein kinase-dependent autophagy mediated the protective effect of sonic hedgehog pa
Aims: Previous study from our lab reported that sonic hedgehog (Shh) pathway plays a protective role in myocardial infar......
Effect of Arsenic Compounds on the Mouse Embryonic Stem Cells Differentiation into Cardiomyocytes in
Arsenic is a known carcinogen;however, there is no information about toxic effects of inorganic arsenic and its intermed......
The protective effects of remifentanil preconditioning against hypoxia reoxygenation injury in cultu
The cardioprotective effects of remifentanil preconditioning (RPC) against ischemia reperfusion injury have been demonst......
Screening and bioinformatics analysis of the specific microRNAs involved in the protective effects o
Ischemic preconditioning (IPC)-mediated cardioprotection has been reported impaired in some pathological conditions 1.Pr......
H+-sensitive proteins mediate extracellular acidification-induced Ca2+ elevation in ventricular card
OBJECTIVE Acidosis-induced [Ca2+]i transients emerged in heart ischemia is an old story.Currently, three mechanisms are ......
As a member of the tissue KLK family, KLK8 has been detected in a variety of tissues and biological fluids.However, the ......
Sphingosylphosphorylcholine modulates autophagy via Lipid raft/PTEN/Akt1/mTOR signaling and inhibits
Autophagy, evoked by diverse stresses including myocardial ischemia/reperfusion (I/R), profoundly affects the developmen......
Reactive oxygen species and Ca2+ signaling during myocardial ischemia/reperfusion injury and protect
Myocardial injury following ischemia/reperfusion (I/R) is a common clinical scenario in patients suffering from ischemic......
Objective microRNAs play an important role in the process of many cardiovascular diseases at the post transcriptional le......
Inhibition of myocardial ischemia/reperfusion injury by exosomes secreted from mesenchymal stem cell
Exosomes secreted by mesenchymal stem cells have shown great therapeutic potential in regenerative medicine.In this stud......
As an optimal solution for patients with end stage cardiac failure,heart transplantation has been applied in clinic for ......
Temporal expressions of cell cycle regulators mRNA during hypertrophic process of H9c2 cells induced
Aim: To observe the mRNA expressions of cell cycle regulators at different time point during the hypertrophic process of......
Temporal expressions of cell cycle regulators mRNA during hypertrophic process of H9c2 rat cardiomyo
Aim: To observe the mRNA expressions of cell cycle regulators at different time point during the hypertrophic process of......
DP2 Deficiency Improves Cardiac Function after Acute MI by Suppressing Cardiomyocytes Apoptosis in M
Rationale:Cardiomyocytes apoptosis contributes significantly to cardiac remolding after acute myocardial infarction (MI)......
Modeling long QT syndrome with cardiomyocytes derived from patient-specific induced pluripotent stem
Aims Inherited long QT syndrome (LQTS) is characterized by QT-interval prolongation and lethal arrhythmia resulting from......
Adverse drug side effect, such as cardiotoxicity, is a major concern in drug development and a major cause of drug withd......
The use of Dox is limited due to its association with cardiovascular complications, which are manifested as acute and ch......
Combination of salvianolic acid A, rosmarinic acid, tetrahydropalmatine and dehydrocorydaline-active
AIM To observe the effects of the main active component combinations of a famous Chinese herbal formula "Shuang Shen To......
Distinct Patterns of Intracellular Ca2+ Release in Specific Cardiacomyocyte Types Derived from hESCs
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Phosphatidylinositol-4,5-bisphosphate (PIP2) is a minor phospholipid component of cell membranes but is an important sec......
Reactive oxygen species contribute to the induction of superoxide dismutase during heat shock in cul
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Knockout of the tumor necrosis factor α receptor 1 gene can up-regulate erythropoietin receptor duri
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Testosterone exerts an important regulation of cardiovascular function through genomic and nongenomic pathways.It produc......
Sphingosylphosphorylcholine promotes the differentiation of sea-1 cells to cardiomyocytes through mo
Resident cardiac stem cell therapy referring to substituting the damaged myocardium with newly regenerated tissue is......
Cardiomyocyte differentiation in vitro system from zebrafish embryos remains to be established.Here,we have determin......
线粒体是细胞能量代谢的重要场所,并介导缺血（氧）诱导的细胞凋亡。存在于线粒体内膜上的线粒体膜通透性转换孔（mitochondrial permeab......
The mechanism of idiopathic ventricular tachycardia originating from the right ventricular outflow tract (RVOT) is not c......
Experimental study on the induction of bone marrow stromal cells differentiating into cardiomyocyte-
Objective:To investigate the feasibility of bone marrow stromal cells (BMSCs) differentiating into cardiomyocyte-like ce......
Objective:To explore the effect of emulsified isoflurane(EI)on apoptosis of anoxia-reoxygenation neonatal rat cardiomyoc......
p42/p44 mitogen-activated protein kinases inhibit atrial natriuretic peptide mRNA transcription in g
Objective:To understand the role ofANP mRNA transcription regulation in gp130-mediated cardiomyocyte hypertrophy, and th......
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Effects of Tensile Stimulation and Electrical Stimulation on the Connexion-43 mRNA Levels of Cardiom
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Protective role of retinoid X receptor in H9c2 cardiomyocytes from hypoxia/reoxygenation injury in r
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的:研究S100B在多柔比星诱导心肌细胞损伤中的表达变化及作用.方法:将体外培养的心肌细胞随机分为对照组,多柔比星损伤组(DOX组)......
目的:探究CTRP3在糖氧剥夺/再灌注(OGD/R)诱导的心肌细胞损伤中的作用及其可能的作用机制。方法:体外培养大鼠心肌细胞H9c2,OGD/R......
Experimental study on the induction of bone marrow stromal cells differentiating into cardiomyocyte-
Objective:To investigate the feasibility of bone marrow stromal cells (BMSCs) differentiating into cardiomyocyte-like ce......
Nonhematopoietic erythropoietin derivative protects cardiomyocytes from hypoxia/reoxygenation-induce
Objective:Carbamylated EPO(CEPO) is a derivative of erythropoietin(EPO) by subjecting it to carbamylation. It does not s......
Effects of captopril and enalaprilat on intracellular Ca~(2+),Na~+ contents and pH in hypoxic and re
探讨卡托普利（Ｃａｐ）和依那普利拉（Ｅｎａ）保护缺氧和复氧心肌细胞作用机制．方法：采用荧光探针结合图象处理技术测定细胞内离子浓度．结果：缺氧和复氧心......
目的：研究长春西汀对心肌细胞钠电流的作用．方法：用全细胞膜片箝技术记录大鼠心肌细胞钠电流．结果：长春西汀可逆性抑制心肌细胞钠电流的......
