DNAmethylation相关论文
miR-30a-5p promotes glomerular podocyte apoptosis via DNMT1-mediated hypermethylation under hyperhom
Abnormal elevation of homocysteine(Hcy)level is closely related to the development and progression of chronic kidney dis......
Crosstalk between CpG Methylation and Polymorphisms (CpG-SNPs) in the Promotor Region of DIO2 in Kas
Objective This study was designed to determine the methylation profile of four CpGs and the genotypes of two CpG-SNPs lo......
In this study, we tested the ability of sodium dehydroacetate (SD) to extend the shelf-life of \'Kyoho\' grape. Amon......
Autoimmune diseases with hematological manifestations are often characterized by chronicity and relapses despite treatme......
目的:研究DNA甲基化在结核分枝杆菌（MTB）裂解物诱导CD4n +T细胞白细胞介素6受体（IL-6R）表达下调中的作用及机制。n 方法:本研......
Objectives It is unclear whether G protein-coupled receptor 61 (GPR61) affecting body weight, plays a role in the associ......
Dynamic profiles of DNA methylation and the interaction with histone acetylation during fiber cell i
Background: Fiber, as the main product of cotton, provides main raw material for the textile industry. Many key factors ......
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辅助生殖技术（assisted reproductive technology，ART）是治疗不孕症的有效方法，但其安全性值得关注。控制性促排卵作用于卵母细胞印记......
Paired box 5 increases the chemosensitivity of esophageal squamous cell cancer cells by promoting p5
Background::Gene promoter methylation is a major epigenetic change in cancers, which plays critical roles in carcinogene......
Roles of MEM1 in safeguarding Arabidopsis genome against DNA damage,inhibiting ATM/SOG1-mediated DNA
Arabidopsis methylation elevated mutant 1 (mem1)mutants have elevated levels of global DNA meth-ylation.In this study,su......
Background and objectives: The occurrence and development of lung cancer are closely linked to epigenetic modification. ......
Effect of Shengmai Yin on the DNA methylation status of nasopharyngeal carcinoma cell and its radior
Shengmai Yin (SMY) is a Chinese herbal decoction that effectively alleviates the side effects of radio-therapy in variou......
Background:Tan sheep, an important local sheep breed in China, is famous for their fur quality. One-month-old Tan sheep ......
目的:构建适用于评估和校准人类生物学年龄的表观遗传学时钟模型。方法:于2019年7月1日至11月30日从广西壮族自治区长寿队列选取18......
砷是一种广泛存在于自然环境中的具有致癌作用的非金属物质。慢性砷暴露会造成全身多器官损伤，因其发病机制不明确、缺乏特效药及早......
With the rising incidence of cardiovascular diseases,the concomitant mortality and morbidity impose huge burdens on qual......
Correlation of DNA methylation patterns to the phenotypic features of Tibetan elite alpinists in ext
High altitude is an extreme environment that imposes hypoxic pressure on physiological processes,and natives living at h......
近年的研究己经揭示出表型可塑性可以通过营养世代遗传.从这个意义上讲,环境诱导的基因调控变化(例如DNA甲基化,即表观遗传变异)会......
DNA methylation changes induced by BDE-209 are related to DNA damage response and germ cell developm
Decabrominated diphenyl ether(BDE-209)is generally utilized in multiple polymer materi-als as common brominated flame re......
Acupuncture has been widely used for treating diseases since the ancient days in China,but the mechanism by which acupun......
DNA Methylation and SNPs in VCX are Correlated with Sex Differences in the Response to Chronic Hepat
The study was conducted to explore the mechanisms of sex differences in the response to chronic hepatitis B (CHB) in ter......
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The effect of diet-induced insulin resistance on DNA methylation of the androgen receptor promoter i
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The aim of this study was to design a molecular assay for the diagnosis of Klinefelter syndrome(KS), based on the detect......
Recent studies have shown signiifcant associations of aberrant DNA methylation in spermatozoa with idiopathic male infer......
Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcin
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DNA methylation plays a role in adipogenesis and myogenesis of myoblasts by regulating transcription
Adipogenesis in muscle attracts more intense interests since it is related to meat quality in animal production.The orig......
Extensive incorporation of engineered nanomaterials(ENMs)into industrial and biomedical applications increases the risks......
INTRODUCTION In mammals,Hypothalamus-Pituitary-Ovary (HPO) axis was one of the key endocrine and reproduction systems,wh......
Intragenic DNA methylation status down-regulates bovine IGF2 gene expression in different developmen
DNA methylation is a key epigenetic modification in mammals, have essential and important roles in muscle development.In......
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Understanding the molecular mechanism of muscle phenotype variation based on the analysis of genome-
In order to understand the skeletal muscle phenotype of animals we used the pig as a model because it formed a number of......
Comparison of DNA methylation in the developing seeds of yellow- and black-seeded Brassica napus thr
Objectives:To help understand theepigenetic regulation of seed coat color in Brassica napus.Methods:Theyellow-seeded rap......
Detection of fetal epigenetic biomarkers through genome-wide DNA methylation study fornon-invasive p
Background: he discovery of fetal cell-free DNA (cff DNA) in maternal plasma during pregnancy provides a new perspective......
Tenderness constitutes one of the main characteristics in beef quality.In this study, a methylome analysis was performed......
DNA methylation alterations in photoperiod-thermo-sensitive male sterile rice PA64S under two differ
Epigenetic modification can occur at a high frequency in crop plants and might generate phenotypic variation without cha......
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Bisphenol A,a synthetic additive used to harden polycarbonate plastics and epoxy resin,is ubiquitous in our dailylife.BP......
为了研究DNA甲基转移酶3A(DNMT3A)在肿瘤发生发展中的作用,探讨DNMT3A调控肿瘤相关基因表达的机制,我们以DNMT3A RNAi 的肝癌细胞......
Methylation-mediated silencing of miR-124 facilitates Chondrogenesis by Targeting NFATc1 under Hypox
Chondrogenic differentiation of mesenchymal stem cells was regulated by different pathways.Sox9 has been regarded as mas......
Objective: Schwann cells(SCs)showed differences in biology before and after peripheral nerve injury.Previous researches ......
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