DEFENSIN相关论文
AMPs（Antimicrobial peptides,AMPs）是一类由特定基因编码的小分子多肽,广泛分布于各种生物中,是生物天然免疫的重要效应分子。家蝇D......
The epididymal β-defensins have evolved by repeated gene duplication and divergence to encode a family of proteins that......
桔小实蝇(Bactrocera dorsalis)(Hendel)隶属于双翅目(Diptera)、实蝇科(Tephritidae),果实蝇属(Bactrocera Macquart),是一种全世......
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A novel Anionic Defensin from Plutella xylostella with Potential Activity Against Bacillus thuringie
Insect Defensins,which are class of small,cysteine-rich antimicrobial peptides primarily active on Gram-positive bacteri......
Molecular Cloning and Function Analysis of the Defensin Gene in the Ixodid Tick,Dermacentor silvarum
Ticks are obligate,blood-feeding ectoparasites which usually parasitize mammals,birds and reptilia,and are among the mos......
The structural similarity between the defensins and scorpion neurotoxins suggests might evolve from a common ancestor.Ho......
Defensins are a major family of antimicrobial peptides expressed predominantly in neutrophils and epithelial cells,a......
AIM:To investigate the protective effect of bifidobacterium in endotoxin-induced intestinal injury in preweaning rats.ME......
Induction of human β-defensin-2 in airway epithelial cells by Streptococcus pneumoniae:involvement o
Human β-definsin-2(hBD-2)is mainly induced by bacterial factors and pro-inflammation mediators in epithelial cells.As t......
AIM: To investigate the genetic background of human defensin expression in type 1 and 2 diabetes.METHODS: Associations b......
防御素是近年来发现的一类内源性小分子多肽,人β-防御素-3(HBD-3)是在银屑病患者皮损组织中首先发现,HBD-3在人体上皮细胞和黏膜......
防御素属于阳离子抗菌肽家族，具有广泛的抗微生物活性、细胞毒性和免疫趋化作用，在先天免疫系统中起着重要作用。近些年，随着防御素抗......
Objective:To investigate the antibacterial properties of lucifensin in maggots of Lucilia sericata after septic injury. ......
AIM: To determine if primary murine colonic epithelial cells (CEC) respond to commensal bacteria and discriminate betwee......
High concentrations of human β-defensin 2 in gastric juice of patients with Helicobacter pylori infe
AIM: Human β-defensin (HBD)-1 and HBD-2 are endogenous antimicrobial peptides. Unlike HBD-1, the HBD-2 expression is au......
Concentrations of α-and β-defensins in gastric juice of patients with various gastroduodenal disease
AIM: To determine the concentration of α-and β-defensins in gastric juice of patients with various gastroduodenal dise......
目前的研究发现克罗恩病(CD)的发病可能与肠道粘膜防御素(defensin),尤其是β防御素1～3(HBD1～3)功能缺陷密切相关,并且应用外源性抗......
Defensin expression in chronic pouchitis in patients with ulcerative colitis or familial adenomatous
AIM:Pouchitis develops in ileoanal pouches in up to50% of patients with ulcerative colitis during the first 10years aft......
Soluble expression of active human β-defensin-3 in Escherichia coli and its effects on the growth of
Background Human β-defensin-3(HBD_3)is an epithelial peptide that has been demonstrated to have a salt-insensitivebroa......
Antimicrobial peptides,including defensins,are essential effectors in host defence and in the maintenance of immune home......
The pathogenesis of both entities of inflammatory bowel disease (IBD), namely Crohn’s disease (CD) and ulcerative colit......
Lactobacillus crispatus M206119 exacerbates murine DSS-colitis by interfering with inflammatory resp
AIM:To investigate the role of Lactobacillus crispatus(L.crispatus) strain China Center for Type Culture Collection(CCTC......
阜阳市局 ￡4a 局长——_MINtkMMtgj’＃lnH＄B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
多形态核中性白细胞(PMN)具有氧化和非氧化两种方式的杀菌机制,非氧化机制是由PMN细胞质中的苯胺兰颗粒的内源抗菌多肽介导的,这......
To establish a cell line for stable expression of human beta-defensin 3 (hBD3). Methods Full length cDNA of hBD3......
目的:探索大蒜素与β防御素3(HBD3)的关系及其在人体抗感染的免疫机制。方法:采用含大蒜素培养液(5 mg/L)培养肺癌A549细胞,通过RT......
从昆虫到人类的多数动物已具备多种肽防御体系,以对抗微生物的入侵及感染。抗微生物肽的治疗作用成为近期的一个研究焦点。一百年......
目的:研究含CpG序列的寡核苷酸(unmethylated CpG motif containing oligodeoxynucleotide,CpG ODN)对人肺腺上皮细胞β防御素-2(h......
Impact and potential mechanism of human α-defensin 1 on low-density lipoprotein oxidation ability of
Objective To explore the role and potential mechanism of humanα-defensin 1 (HNP-1) on low-density lipoprotein (LDL) oxi......
原虫为单细胞真核生物,致病性原虫对人类健康和畜牧业生产造成了严重危害。目前,抗原虫治疗仍以化学药物为主,但由于其带来严重的......
防御素(defensin)是一类相对分子质量为(4.0~5.0)×103且富含氨基酸残基的阳离子抗菌肽。对革兰阴性菌、分枝杆菌、真菌等有很强的......
Expression Comparisons of Pathogenesis-Related(PR) Genes in Wheat in Response to Infection/Infestati
Expression profi les of ten pathogenesis-related(PR) genes during plant defense against Fusarium, Yellow dwarf virus(YDV......
Objective: To initially explore the application of proteome technologies in study of serum, to establish two-dimen-siona......
With the rapid increase of antibiotic-resistant pathogens and the decline of discovery and development of new antibiotic......
Cellceutix公司宣布已收到其新抗生素Brilacidin的伦理委员会的初步核准函,进行证实概念的Ⅱ期临床试验,用Brilacidin治疗溃疡性直......
防御素(defensin)是一类富含半胱氨酸的内源性抗微生物小分子多肽,人防御素可分成α-、β-和θ-防御素3种。除广谱抗微生物活性外,......
目的观察重组小鼠β防御素3(r MBD3)对甲型流感病毒感染小鼠的保护作用。方法以10 mg·kg-1·d-1r MBD3腹腔注射3月,观察小鼠的一......
抗菌肽是生物体防御系统产生的一类多肽.越来越多的研究表明抗菌肽不仅能够直接抑制和杀灭病原微生物,同时具有多种免疫调节活性,......
Plant defensins are small, basic cysteine-rich peptides that play important roles in disease resistance. A gene, designa......
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,EGFR-targeting, β-defensin-tailored fusion protein exhibits high therapeutic efficacy against EGFR-
Defensins play an essential role in innate immunity.In this study,a novel recombinant β-defensin that targets the epide......
防御素是生物界较广泛存在的一类抗微生物和一些恶性细胞的短肽。它通常是２９～５４个氨基酸组成，通过至少６个保守半胱氨酸构成三对二硫键使肽......
Expression of rabbit defensin NP-1 gene in transgenic tobacco plants and its activity against bacter
A cDNA_derived 200 bp fragment encoding a rabbit defensin NP_1 mature peptide was ligated into the GUS_less pBI121 to yi......
目的探讨沙门菌对小鼠胃癌细胞MFC增殖及β-防御素-2(mouseβ-defensin,m BD-2)表达的影响。方法将不同浓度(10、10~2、10~3和10~4......
目的诱导毕赤酵母(Pichia pastoris)分泌表达表达致倦库蚊(Culex quinquefasciatus)防御素(defensin)成熟肽,为进一步研究致倦库蚊......
目的诱导毕赤酵母(Pichia pastoris)分泌表达表达致倦库蚊(Culex quinquefasciatus)防御素(defensin)成熟肽,为进一步研究致倦库蚊......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
防御素是一种富含半胱氨酸，低分子量的阳离子抗菌肽。人类母乳中具有相当高浓度的防御素，母乳中的防御素不仅具有抵抗各种病原微生物......
