Signaltransduction相关论文
<正>Many phytohormones play essential roles in coordinately regulating biological processes in plant growth and...
皮肤鳞状细胞癌的发病机制复杂,晚期治疗手段缺乏。本文综述磷脂酰肌醇3-激酶/蛋白激酶B/哺乳类动物雷帕霉素靶蛋白(PI3K/Akt/mTOR)信......
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Therefore, exploring the mechanism of CVDs an......
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Pingchuan formula (平喘方) improves allergic asthma in mice through inhibiting nuclear factor-kappa B/m
OBJECTIVE:To examine the role and decipher the mechanism of Pingchuan formula(平喘方,PCF)in treating allergic asthma.MET......
Signal transduction is an important and basic mechanism to cell life activities.The stochastic state transition of recep......
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Identification of Genes Required for Nonhost Resistance to Xanthomonas oryzae pv.oxyzae Reveals Nove
Nonhost resistance is a type of resistance shown by an entire plant species against all isolates of a microbial species,......
Expressed sequence tags in cultivated peanut (Arachis hypogaea L.) : discovery of genes in seed deve
Although an important oil crop, peanut has only 162,030 expressed sequence tags (ESTs) publicly available, 86,943 of whi......
A protein phosphatase in Arabidopsis regulates root growth and root hair development through modulat
ROS (reactive oxygen species) homeostasis is critical for normal root development in plants,and a threshold level of ROS......
Mutual Information Flow between Beneficial Microorganisms and the Roots of Host Plants Determined th
Modern agriculture is facing new challenges in which ecological and molecular approaches are being integrated to achieve......
Effect of Qinge Pill on Osteoblasts Proliferation and the Expression of Signal Pathway Protein in in
Objective Investigate the expression of MMP3-OPN-MAPK pathway proteins in the osteoblasts and the mechanism of the expre......
Lockage of Notch-1/Hes-1signaling can be a contributing factor to actue lung ingury progression in s
目的 The regulation of Notch/Hes signaling in inflammatory responses has become a research highlight in recent years.But......
Aim: Toll-like receptors (TLRs) are major family of pattern-recognition receptors and play a crucial role in innate immu......
The effects of morphine on the presynaptic glutamate release in the pyramidal neurons of the basolat
By sustained activation of opioid receptors, chronic opioids cause analgesic tolerance, physical dependence, and opioid ......
G protein-coupled receptors(GPCRs)are major players in cell communication.Growing evidence has indicated that some GPCRs......
mGluR5-PLCbeta4-PKCbeta2/PKCgamma pathways in hippocampal CA1 pyramidal neurons in pilocarpine model
In pilocarpine induced status epilepticus (PISE) in metabotropic glutamate receptor 5 (mGluR5) knock-out (mGluR5-/-) and......
Regulatory T (Treg) cells characterized by the transcription factor FoxP3 have a fundamental role in the establishment a......
Genetic Manipulation of Human Embryonic Stem Cells:An Efficient Way in Studying Early Human Neural D
Most of our understandings about human neural lineage development were directly translated from other species,such as ch......
Spontaneous Osteogenic Differentiation of Mesenchymal Stem Cells on Electrospun Nanofibrous Scaffold
In bone tissue engineering,stem cell-scaffold constructs play an important role in bone regeneration.Desirable biomimeti......
Neuroprotective effects of pioglitazone is associated with PPARγ-mediated inhibition of NF-κB signal
Objective To investigate the neuroprotective actions of pioliotazone (Piog) and the effects of Piog-mediated PPART activ......
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The effect of CD137-CD137 ligand interaction on phospholipase C signaling pathway in human endotheli
Background We previously reported the emerging role of CD137-CD137L interaction in inflammation and atherosclerosis.The ......
Glycosylphosphatidylinositol-anchored proteins as chaperones and co-receptors for FERONIA receptor k
The Arabidopsis receptor kinase FERONIA (FER) has been characterized as a critical multifunctional regulator in many asp......
Phosphoinositide-Specific Phospholipase C Isoform 3 (PLC3) and PLC9 Function Redundantly in Thermoto
The heat stress response provides an important adaptation,enabling plants to survive challenging environmental condition......
Investigation of the Molecular Mechanisms of Anti-Tumour Effects Of Some Triterpenoidsfrom Ganoderma
Ganoderma lucidum,a traditional Chinese medicine,is well known as a modulator of functions of the immune system as well ......
Regulator of G-protein signaling 10 negatively regulates cardiac remodeling by blocking MEK-ERK1/2 s
Regulator of G-protein signaling 10 (RGS10) is an important member of the RGS family and produces biological effects in ......
Involvement of CGRP-RCP (calcitonin gene-related peptide receptor component protein) in signal trans
Static pressure derived from blood flow significantly stimulates vascular smooth muscle cells (VSMC) proliferation via t......
The delayed rectifier potassium current (IK) is a major outward current responsible for ventricular muscle action potent......
Controlled and Cardiac-Restricted Overexpression of the Arginine Vasopressin V1A Receptor Causes Rev
Background Arg8]-vasopressin (AVP) activates 3 G-protein–coupled receptors: V1A,V2,and V1B.The AVP-V1A receptor is the ......
Optical manipulation appears to be a powerful tool for spatiotemporally controlling various cellular functions....
Bispecific Aptamer Induced Artificial Protein-Pairing:A Strategy forSelective Inhibition of Receptor
Cell surface receptors play a critical role in modulating intracellular signal transduction,making them important drug t......
Identification of cell-specific signaling of estrogen receptor using a structural-based design strat
In both women and men,estrogens are important mediators of many physiological functions related to the reproductive and ......
Investigation of regulating effects of copper chelators on the intracellular redox signaling by inhi
The imbalance expressing of Cu/Zn superoxide dismutase (SOD1) in vivo will cause intracellular oxygen reduction signal t......
Biologically active natural products are not only one of the major resources of pharmaceuticals,but also bridges between......