TETRAHYDROISOQUINOLINES相关论文
ConformationallyConstrained Tetrahydroisoquinolines:Design,Synthesis and SAR Study as PARP-1Inhibito
Poly(ADP-ribose) polymerase-1(PARP-1)(ADP,adenosine diphosphate) is a 113kDanuclear protein that is involved in the sign......
Efficient and Practical Syntheses of Enantiomerically Pure (S)-(-)-Norcryptostyline Ⅰ, (S)-(-)-Norcr
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Synthesis and cytotoxicity of dinuclear platinum(Ⅱ) complexes of(1S, 3S)-1,2,3,4-tetrahydroisoquinol
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为寻找新型心血管药物,将钾通道阻滞剂分子中常见的磺酰胺基引入了苄基四氢异喹啉的4‘位,设计合成了10个1-(4-磺酰胺基)苄基四氢异喹啉化合物......
研究发现某些异喹啉类化合物具有较好的心血管活性,N胺乙酰基取代的苄基四氢异喹啉化合物对二氢吡啶(DHP)受体有较好的亲和力〔1〕.据报道......
为寻找新的高效、低毒、副作用小的心血管药物,设计合成了12个苯甲酰乙基四氢异喹 类衍生物,并进行了初步药理实验。......
目的1设计合成新型四氢异喹啉类化合物,寻找具有抗真菌和抗生育双重作用的化合物,为研究具有抗真菌作用的避孕药物提供先导结构。方......
Determination of Enantiomeric Composition of Substituted Tetrahydroisoquinolines Based on Derivatiza
A method for the analysis of the optical purity of a series of chiral substituted tetrahydroisoquinolines (THIQs) was de......
1-Chloromethyl-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-sulfonic acid amide, a derivative of tetr
Tetrahydroisoquinolines are known to have various biological effects, including antitumor activity. This study investiga......