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Since the early 2000s, the popularity of zebrafish in in vivo drug screening has shown a substantial increase. The zebra......

Hematopoietic stem and progenitor cells (HSPCs) are able to self-renew and can give rise to all blood lineages throughou......

Hydrostatic pressure is one of the main factors limiting the vertical range of marine organisms.However,little is known ......

The Metronidazole (MTZ)/nitroreductase (NTR)-mediated cell ablation system is the most commonly used chemical-genetic ce......

Objective To determine if ARHGEF10 has a haploinsufficient effect and provide evidence to evaluate the severity, if any,......

Mechanistic target of rapamycin (mTOR) sig-naling governs important physiological and pathological processes key to cell......

Objective: To compare the differences in behavior of sleep deprivation models in caffeine and light induced zebrafish. M......

Objective::The zebrafish is an excellent model for studying gene function in auditory system development. n Pou4f3 ......

Tripterygium wilfordii multiglycoside(GTW)is a commonly used compound for the treatment of rheumatoid arthritis(RA)and i......

Objective:To investigate the pro-angiogenic effects of paeoniflorin (PF) in a vascular insufficiency model of zebrafish ......

Objective:To determine the effects of Hydrangeae Dulcis Folium (EHDF) on physical stress,changes in the whole-body corti......

Several chemical compounds can restore pigmentation in vitiligo through mechanisms that vary according to disease etiolo......

Schisandra chinensis,a traditional Chinese medicine (TCM),has been used to treat sleep disorders.Zebrafish sleep/wake be......

Angiogenesis is a crucial process in the development of inflammatory diseases, including cancer, psoriasis and rheumatoi......

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In the present study, zebrafish embryos were used to assess the neurotoxicity of di-n-butyl phthalate (DBP), diethyl pht......

Candida albicans is a major fungal pathogen in humans.Several C.albicans virulence factors have been identified, includi......

Pyraoxystrobin is a novel strobilurin fungicide with excellent and broad spectrum antifungal efficiency.However,the toxi......

For a virus,to inhibit host interferon(IFN)expression is indispensable for its proliferation,since IFN is crucial for ho......

Interferon regulatory factor (IRF) 10 belongs to IRF family and exists exclusively in bird and fish.Most IRFs have been ......

Mouse Prdm1,also known as Blimp1,plays important roles in maturation and survival of lymphoid cells,as well as in organo......

Objective The circadian clock plays a vital role in physiology and behavior such as the sleep-wake cycle and blood press......

Objective Axon-wrapping myelin sheath formed by oligodendrocytes(OLs)is essential for proper functions of the nervous sy......

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Learning from others in a group of individual has a distinct evolutionary advantage....

Struggling for survival and reproduction,animals need to extract salient information from superfluous sensory signals of......

Objective Despite the use of anesthetic drugs in clinical applications for nearly 170 years,it is still unclear whether ......

ObjectiveSingle-cell electroporation is especially useful for studies requiring single cell resolution,such as imaging s......

The habenular nuclei(habenulae)are highly conserved bilaterally paired nuclei which develop in the dorsal diencephalon o......

Appropriate preference for light or dark is crucial for animals survival,but the underlying circuit mechanism is largely......

Given the severe situation of world-wide particulate matter air pollution, it is urgent to explore the combined biologic......

The brain is an excessively vascularized organ and requires an integrative vascular system to maintain the microenvironm......

Site-directed gene modification is an important method in gene function research.It can also be applied in many fields,s......

Circadian rhythm orchestrates a wide variety of physiological and behavioral processes of animals to adapt to cyclic env......

Vertebrate brains exhibit astounding complexity and intricate interconnection.We have been using the zebrafish model to ......

Attention-Deficit Hyperactivity Disorder(ADHD)is one of the most prevalent psychiatric disorders in children and adults....

The biophysical properties of intracellular diffusion and trafficking of soluble proteins in the axon of a living organi......

A variety of external stimuli and internal psychological states,collectively called stressors,activate the hypothalamic-......

Cilia are hair like structures protruding from cell surface and play diverse biological functions.Defects in ciliogenesi......

Cilia/flagella are conserved eukaryotic organelles involving in cell motility, environment sensory and embryo developmen......

Dysregulation of ribosome biogenesis causes human diseases, such as Diamond-Blackfan anemia, 5q minus syndrome and bone ......

The melanocortin-4 receptor (MC4R) is an unusual G-protein coupled receptor that plays a critical role in energy homeost......

The sensitive tyrosine hydroxylasegreen fluorescent protein (THGFP) transgenic zebrafish was originally developed and ap......

Objective To investigate the change patterns of Histone 3 lysine 9 acetylation (H3K9ac) and the expression profile of hi......

Objective—Vascular endothelial growth factor A(VEGFA)regulates both vasculogensis/angiogenesis and heart development.We......