folicacid相关论文
本课题以 2,5,6- 三氨基 -4- 羟基嘧啶硫酸盐，三氯丙酮为原料，合成蝶呤类杂质，研究了合成过程中物料摩尔比、反应温度、反应时间、反......
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Objective: To investigate the effects of folic acid on testicular oxidative damage in sodium fluoride-induced male Wista......
Randomized Double-Blind Clinical Trial of Moluodan(摩罗丹) for the Treatment of Chronic Atrophic Gastri
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Objective: Iron oxide(Fe3O4)nanoparticles(NPs)have been generally used as T2-negative magnetic resonance(MR)imaging cont......
Preparation and functional characterisation of tumor-targeted folic acid-chitosan conjugate nanopart
In recent years,chitosan microspheres have attracted more and more attention as a carrier for drug delivery because chit......
Application of nanobiotechnology to deliver therapeutic drugs selectively to diseased sites with imp
A number of drugs only give rise to limited clinical response when causing remarkable toxicities due to wide distributio......
Dendrimer-Entrapped Gold Nanoparticles Modified with Folic Acid for Targeted Gene Delivery Applicati
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Ursolic acid(UA)as a nature product exhibits high anti-cancer efficiency and low toxicity features.However,the inefficie......
Targeted intracellular release of anticancer peptide in cervical cancer cells with functionalized me
NuBCP-9,a peptide that can bind Bcl-2 and convert its anti-apoptosis function,was reported to play an important role in ......
Recombinant adeno-associated virus(rAAV)vectors are extremely promising gene therapy vectors,which has been widely used ......
Efficient antisense oligonucleotide delivery via non-covalent complexes of folic acid and modified p
In the field of gene delivery,the development of vectors with high transfection efficiency and low toxicity is of critic......
Gold nanostars(AuNSs)have been extensively studied as photothermal conversion agents for cancer therapy due to their hig......
Folic Acid-Modified PEGylated Dendrimer-Entrapped Gold Nanoparticles for In Vitro and In Vivo Specif
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Multifunctional polyethylenimine-based nanoplatform for targeted anti-cancer drug delivery to tumors
Hyperbranched polyethylenimine (PEI) possessing good water solubility has been selected as an effective vehicle to encap......
Folate-bovine serum albumin functionalized polymeric micelles loaded with superparamagnetic iron oxi
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We report a new usage of folic acid-modified dendrimer-entrapped gold nanoparticles (Au DENPs-FA) as nanoprobes for in v......
Constrution of Multifunctional Nanoparticles and Application for Bimodal Imaging and Targeted Drug D
Obiective To construct multifunctional nanoparticles and to evaluate its properties of Fluorescence imaging(FLI),magneti......
Effects of Omega-3 polyunsaturated fatty acids combined with folic acid and vitamin B6 on plasma lip
Objective 1.To study the Omega-3 fatty acids combined folic acid,VB6 supplement improve the blood lipid,the effect of ho......
Photoacoustic imaging is a noninvasive imaging method.It has various advantages such as good resolution and high contras......
Homocysteine lowering by folic acid supplement reversed hyperhomocysteinemia aggravated angⅡ-induced
Abdominal aortic aneurysm (AAA), defined as a 50% increase in external diameter of the abdominal aorta, is one of the le......
Postsynthetic modifications of zinc-carboxylate nanoscale metal-organic frameworks for targeted drug
Given the high potential of metal-organic frameworks (MOFs) to be used as delivery carriers for drug molecules, it is cr......
Folic Acid-Functionalized Ultra-Small Nanographene Oxide for Multimodal Nuclide/Optical Molecular Im
Graphene oxide (GO) is an emerging member of carbon-based nanomaterials and has exhibited a great application potentials......
neural tube defects,is a kind of serious congenital birth defects in the central Nervous system disease and is one of th......
In vitro targeting behaviors of Folate-conjugate Pluronic F127/poly (lactic-co-glycolic) nanoparticl
Novel Pluronic F127/poly (lactic-co-glycolic) block copolymer PLGA-F127-PLGA and Folated FA-F127-PLGA were synthesized a......
To investigate the damaging effect of hyperhomocysterinemia (HHcy) on cerebral cortex and hippocampus in apolipo-protein......
Several reports demonstrated that mice exposed to LPS at middle gestational stage caused neural tube defects(NTDs).The p......
Folid acid supplementation during pregnancy protects against lipopolysaccharide-induced teratogenici
Lipopolysaccharide (LPS) is associated with adverse developmental outcomes,including preterm delivery,fetal death,terato......
Several reports demonstrated that mice exposed to LPS at middle gestational stage caused neural tube defects (NTDs).The ......
PT-PP54:Determination Of Folic Acid By Molecularly Imprinted Polymer-Quartz Crystal Microbalance Sen
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研究了叶酸修饰硒化镉掺杂二氧化钛(FA-CdSe-TiO2)的纳米颗粒体外光动力(PDT)灭活HL60细胞的作用效果，探讨了叶酸修饰增强CdSe-TiO2......
Prospects for improving future mental health of children through prenatal maternal micronutrient sup
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目的探讨肠道菌群、叶酸及两者的关联性对首发未用药精神分裂症（SCZ）患者精神症状的影响。方法选取2018年3月至2019年12月郑州大学第......
AE-PP22Determination Of FoHc Acid By Molecularly Imprinted PolymerQuartz Crystal Microbalance Sensor
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目的探讨叶酸联合甲钴胺治疗伴高同型半胱氨酸血症急性脑梗死的效果及安全性。方法100例伴高同型半胱氨酸血症急性脑梗死患者按照......
通过研究铅对大鼠中枢神经元的损伤以及应用叶酸后的影响，探讨了叶酸对铅中毒条件下中枢神经元的保护作用。将健康清洁级初断乳3周......
目的 观察慢性肾功能衰竭（CRF）维持性血液透析（HD）患者血浆总同型半胱氨酸（tHcy)的影响因素和大剂量叶酸治疗是否可以纠正其高同型半胱......
Folic acid supplementation attenuates hyperhomocysteinemia-induced preeclampsia-like symptoms in rat
Folic acid participates in the metabolism of homocysteine and lowers plasma homocysteine levels directly or indirectly. ......
目的建立高效液相色谱-串联质谱法同时定性和定量分析复合维生素片中叶酸和生物素的方法。方法样品用水溶液溶解,经Eclipse C18色......
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Folic acid contributes to peripheral nerve injury repair by promoting Schwann cell proliferation, mi
After peripheral nerve injury, intraperitoneal injection of folic acid improves axon quantity, increases axon density an......
Clinical variations of serum levels of ferritin, folic acid and vitamin B12 in acute leukemia patien
Acute leukemia is one of the most common hematologic malignancies and its exact mechanism of development is unknown yet.......
目的观察依那普利叶酸片治疗H型高血压的疗效。方法将196例H型高血压合并颈动脉硬化的患者，按数字表法随机分为依那普利叶酸片组(依......
目的探讨叶酸联合甲钴胺用于脑小血管病伴高同型半胱氨酸(Hcy)血症的临床效果。方法选择聊城市第二人民医院2015年1月至2016年12月......
目的:通过检测有不良孕产史育龄人群的红细胞叶酸与正常人群红细胞叶酸水平,了解叶酸缺乏和不良孕产史之间的关系.方法:2013年1月～2......
目的:探讨叶酸代谢关键酶基因MTHFR C677T、A1298C和MTRR A66G多态性在育龄女性中的分布特征,并分析不同的遗传特征对外周血叶酸、......
目的：进一步研究和探讨孕产妇补充小剂量叶酸对于预防胎儿出生缺陷的临床疗效观察。方法：与某三甲妇幼保健院合作，对在2011年12月至20......
