mammaliantargetofrapamycin相关论文
在获得n Bone杂志的授权后，本文对该刊发表于2019年2月的文章[Wu J, Wang A, Wang X, et al. Rapamycin improves bone mass in......
Celastrus orbiculatus Extracts Inhibit Human Hepatocellular Carcinoma Growth by Targeting mTOR Signa
Objective:To characterize the molecular mechanism underlying the antineoplastic activity of Celastrus orbiculatus Thunb.......
Cadmium induction of reactive oxygen species activates the mitochondrial and AKT/mTOR pathways, lead
Cadmium (Cd) , a widely toxic metal, induces apoptosis in neuronal cells.In our previous study, we found that Cd induced......
Cadmium induction of reactive oxygen species activates the mitochondrial and AKT/mTOR pathways, lead
Cadmium (Cd), a widely toxic metal, induces apoptosis in neuronal cells.In our previous study, we found that Cd induced ......
Hyperoside inhibits cytoskeleton reorganization and cell motility in osterosarcoma cells by suppress
Osteosarcoma cells utilize their intrinsic migratory ability to invade adjacent tissues and the vasculature, and ultimat......
Celastrol prevents cadmium-induced neuronal cell death by blocking mitochondrial ROS inactivation of
We have recently reported that celastrol prevents cadmium(Cd)-induced neuronal cell death by inhibiting Cd-activation of......
This paper discusses about the effects of intensive training and tapering on myocardium mammalian target of rapamycin(mT......
Inhibition of calcineurin in the prefrontal cortex induced depressive-like behavior through mTOR sig
Rational Although it has been recognized that inhibition of calcineurin induced depressive-like behavior, the underlying......
Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis
The mammalian target of rapamycin (mTOR) signaling pathway is upregulated in the pathogenesis of many cancers.Arachidoni......
In the adult mammalian brain, new neurons generated by self-renewing neural stem/progenitor cells (NSCs) can be found in......
Role and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like m
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Accelerated Autophagy of Cecal Ligation and Puncture-Induced Myocardial Dysfunction and Its Correlat
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A Study on the Mechanism of the Protective Effect of GuangeFang on Sepsis-Associated Acute Kidney In
Objective: The objective of this study was to explore the mechanism of Guan Gefang (GGF) ; raw rhubarb 30 g, cassia arbo......
氯胺酮是一种离子型谷氨酸能N-甲基-D-天冬氨酸受体（glutamatergic N-methyl-D-aspartate receptor, NMDAR）拮抗剂，具有快速且持久的......
脓毒症的发生、发展及预后与机体免疫调控密切相关，免疫代谢是近年来脓毒症免疫干预的研究热点。AMP活化蛋白激酶(AMP-activated pr......
Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt s
Rapamycin treatment has been shown to increase autophagy activity and activate Akt phosphorylation, suppressing apoptosi......
在全球范围内，肿瘤的致死率仍然居高不下，如何加强肿瘤治疗及改善患者的生存质量仍是目前关注的焦点和亟需解决的问题。分子靶向治疗......
哺乳动物雷帕霉素靶蛋白（ mTOR）是细胞内许多重要信号转导通路的枢纽，参与多种生理与病理过程（如细胞增殖、细胞周期调控、细胞迁移等），......
目的 探讨小分子RNA干扰雷帕霉素靶蛋白(mTOR)基因表达对百草枯致大鼠肺纤维化的影响.方法 体外培养人胚肾细胞HEK-293,构建mTOR小......
In order to evaluate the effectiveness of everolimus vs.rapamycin in the treatment of diabetic nephropathy,8-week old di......
目的 探讨哺乳动物雷帕霉素靶蛋白(mTOR)信号通路与间变性淋巴瘤激酶(ALK)阳性淋巴瘤的关系.方法 采用Western blot法分析雷帕霉素......
