singlenucleotidepolymorphism相关论文
目的 对43个SNP遗传标记的复合检验体系进行法医学应用评估.方法 采用MALDI-TOF-MS技术检验华东地区123名汉族无关个体在43个SNP位......
目的：:分析n RASGRF1基因顺式调控元件中单核苷酸多态性与甘肃地区近视人群的相关性。n 方法：:系列病例对照研究。选取2018......
Fas -670 A/G polymorphism predicts prognosis of hepatocellular carcinoma after curative resection in
Background: Apoptosis, also called programmed cell death, is a genetically controlled process against hyperproliferation......
Asian cultivated rice shows allelic variation in sodium transporter, OsHKT1;5, correlating with shoot sodium exclusion (......
宫颈癌是女性最常见的恶性肿瘤之一。目前认为，宫颈癌表现为从宫颈上皮内病变到侵袭性癌过渡的连续过程。流行病学证据表明单核苷酸......
Antipsychotic-induced weight gain (AIWG) is a common adverse effect of this treatment,particularly with second-generatio......
Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheime
To evaluate whether the polygenic profile modifies the development of sporadic Alzheimer\'s disease (sAD) and patholog......
Aim: To complete comprehensive haplotype analysis of USP26 for both fertile and infertile men. Methods: Two hundred infe......
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Background:Noise-induced hearing loss(NIHL)is a common occupational disease that represents an irreversible hearing dama......
Cardiovascular Damage in Lead-exposed Workers:Assessing the Association between Polymorphisms in CCM
Objectives Evaluate blood pressure in relation to early cardiovascular damage in workers exposed to lead,and explore the......
Cardiovascular Damage in Lead-exposed Workers:Assessing the Association between Polymorphisms in CCM
[Objectives]Evaluate blood pressure in relation to early cardiovascular damage in workers exposed to lead,and explore th......
Comparison of linkage disequilibrium and effective population size for Landrace and native pig breed
The extent of linkage disequilibrium (LD) and effective population size in a closed nucleus herd of Landrace purebred an......
Development and application of single nucleotide polymorphism markers in the polyploid Brassica napu
Single nucleotide polymorphisms (SNPs) are currently the important classes of genetic markers for major crop species.It ......
INTRODUCTION Genome-wide association studies (GWAS) typically using single nucleotide polymorphism (SNP) as the basic un......
Linkage disequilibrium (LD),which is the non-random association of alleles at different loci,has received a considerable......
Fructans are major nonstructural carbohydrates in wheat(Triticum aestivum L.).Fructan 1-fructosyltransferase(1-FFT)is th......
Genetic dissection of root system architecture of oilseed rape from a large germplasm collection und
Oilseed rape(OSR,Brassica napus L.)is one of the most important oil crops,serving as a source of food,feed and fuel.Low ......
Genetic Polymorphism of MyoG Gene and its Relationship with Meat Quality Traits in Chinese Cattle Po
In this study, we determined the associations between gene-specific single nucleotide polymorphisms (SNP) in MyoG gene, ......
Haplotype Analysis of TLR4 Gene and Its Effects on Milk Somatic Cell Score in Chinese Commercial Cat
Bovine mastitis is a very complex and common disease of dairy cattle and a major source of economic losses to the dairy ......
Objective Lumbar disc degeneration (LDD) is a well-known age related clinical syndrome, a subset of intervertebral disc ......
Lumbar disc degeneration (LDD) impairs the structure and function of lumbar disc, and contributes to low back pain (LBP)......
Objective Objective: To study the correlation between adenomatous polyposis coli(APC)gene 3 untranslated region(UTR)sing......
Single nucleotide polymorphisms within genes in NF-κB,TGF-β and JNK signaling pathways are associate
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Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer r
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Object The biological function of ZNF804A rs1344706, the first genome-wide supported risk variant of schizophrenia, rema......
The effect of the dopamine D4 receptor-616 C/G polymorphism on gray matter volume and functional con
OBJECTIVE To determine whether the 616 C/G single nucleotide polymorphism (SNP) in the dopamine D4 receptor (DRD4) promo......
Association study of POLB polymorphisms with Systemic lupus erythematosus in a Chinese Han populatio
Objective: A large scale replication study based on genome wide association study (GWAS) has implicated IκB kinase β (......
Establishment of a modified high resolution melting assay based on allele-specific-extension to dete
Objective To establish a modified high resolution melting assay based on allele-specific-extension(ASE.HRM) to determine......
Objective: To study the association of the ITPKC gene SNP rs28493229 with Kawasaki disease(KD)susceptibility and formati......
Alzheimers disease (AD) is a common neurodegenerative disorder characterized by progressive cognitive dysfunction and me......
The association study in the diversity of two SNPs sites of β2-AR and EH of Chinese Han population i
Aim: To analyze the diversity of 46 and 79, the two single nucleotide polymorphism (SNPs) sites of β2-AR coding regions......
Using Genome-Wide SNP Microarrays for the Rapid Diagnosis of Copy Number Variation and Uniparental D
Copy Number Variation (CNVs) can be identified via single-nucleotide polymorphism (SNP)-based chromosomal microarray ana......
Pre-eclampsia is the most common complication in obstetric in pregnant women,but the real pathogenesis is still poorly u......
Rs1495741 as a tag single nucleotide polymorphism of N-acetyltransferase 2 acetylator phenotype asso
Objective: Rs1495741 has been identified to infer N-acetyltransferase 2 (NAT2) acetylator phenotype,and to decrease the ......
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A polymorphism in GAS5 promoter impacts efficacy of cytarabine-based chemotherapy in Chinese AML pat
OBJECTIVE SNPs in IncRNAs may alter the expression or secondary structure of IncRNAs and then impact their functions.Whe......
Methylenetetrahydrofolate reductase C677T polymorphism predicts response and time to progression (TT
Objective: The aim of this study was to investigate the relationship between the Methylenetetrahydrofolate reductase (MT......
Serum and cerebrospinal fluid levels of transthyretin in Lewy body disorders with and without dement
Parkinson’s disease (PD) without (non-demented,PDND) and with dementia (PDD),and dementia with Lewy bodies (DLB) are su......
Objective In prenatal diagnostics, both microarray comparative genomic hybridization (array CGH) and single nucleotide p......
No association between catechol-O-methyltransferase Val158Met polymorphism and susceptibility to pre
Background Catechol-O-methyltransferase (COMT) is a key enzyme involved in catecholamine and estrogen degradation and ha......
Association of HSG/Mfn2 Gene polymorphisms with essential hypertension in northern Han Chinese popul
Background Hyperplasia suppressor gene/Mitofusion-2 (HSG/Mfn2) is a novel hypertension-related gene, which can inhibit v......
Association of a functional polymorphism in the MMP-3 gene with moyamoya disease in Chinese Han popu
Background: Moyamoya disease (MMD) is an uncommon cerebrovascular disease characterized by progressive stenosis of the i......
Fine-Mapping of ABO Gene Identifies Two Novel SNPs Associated With Large Artery Atherosclerotic Stro
Background: Recently,a single nucleotide polymorphism (SNP) rs505922 in ABO gene,was related to large artery atheroscler......
Concomitant use of proton-pump inhibitors and clopidogrel is not associated with adverse outcomes af
Aim: Conflicting data exist as to whether proton-pump inhibitors (PPIs) diminish the efficacy of clopidogrel.We,therefor......
Osteoporosis is an inherited complex disease with high risk and morbidity.Previous studies have demonstrated that genes ......
Background: Keratoconus normally occurs as a sporadic disease.Although different studies have found sequence variants of......
