Several genes involved in ginsenoside biosynthesis have been identified, providing the possibility to exploit and utilize these genes.Here, we described our works in this respect.Our research indicates that antisense repression of CAS gene can improve the ginsenoside accumulation levels in Panax ginseng hairy roots.We also express the DS gene in yeast, resulting in an engineered yeast capable of producing dammarenediol.Our work on plantlet regeneration from P.ginseng hairy roots was also discussed.