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  5. Activation of the AMPK-ULK1 pathway plays an important role in autophagy during prion infection

Activation of the AMPK-ULK1 pathway plays an important role in autophagy during prion infection

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：redghy
【摘 要】
：
Objective: AMPK is a serine/threonine protein kinase that acts as a positive regulator of autophagy by phosphorylating ULK1 at specific sites.
【作 者】
：
Hui Wang Xue-Yu Fan Chan Tian Lu-Bin Zhang Yang-Jing Zhao Qi-Xiang Shao Xiao-Ping Dong 
【机 构】
：
江苏大学;中国疾病预防控制中心 中国疾病预防控制中心
【出 处】
：
中国免疫学会第十届全国免疫学学术大会
【发表日期】
：
2015年10期
【关键词】
：
AMPK ULK1 autophagy prion scrapie mTOR LC3 
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　　Objective: AMPK is a serine/threonine protein kinase that acts as a positive regulator of autophagy by phosphorylating ULK1 at specific sites.
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