【摘 要】
：
Modulation of signaling pathways and gene expression is an important approach in the treatment of autoimmune and inflammatory disorders.This presentation will focus on the development of drugs that in
【机 构】
：
Inflammation, Autoimmunity & Transplantation Research Roche Palo Alto, LLC, USA
【出 处】
：
2005 WHTS3rd Annual Congress of International Drug Discovery
论文部分内容阅读
Modulation of signaling pathways and gene expression is an important approach in the treatment of autoimmune and inflammatory disorders.This presentation will focus on the development of drugs that inhibit critical protein targets that control the immune response.Particularly the methodology to assess the effect of compounds in biochemical,cellular models, and diseased tissues to understand the efficacy and safety of drugs will be highlighted in several vignettes.
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