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紫杉醇是靶向肿瘤微管的细胞毒类抗肿瘤药物，临床上广泛应用于各种肿瘤的治疗。紫杉醇在阻断肿瘤细胞有丝分裂的同时，对正常组织细胞也有一定的毒副作用，引起嗜中性白血球减少、呕吐、腹泻等不良反应。
肿瘤靶向紫杉醇-多肽偶合物的合成与生物活性研究
【摘 要】
：
紫杉醇是靶向肿瘤微管的细胞毒类抗肿瘤药物，临床上广泛应用于各种肿瘤的治疗。紫杉醇在阻断肿瘤细胞有丝分裂的同时，对正常组织细胞也有一定的毒副作用，引起嗜中性白血球减少、呕吐、腹泻等不良反应。
【机 构】
：
山东大学药学院有机化学研究室,济南 250012
【出 处】
：
2015年全国药物化学学术会议暨第五届中英药物化学学术会议
【发表日期】
：
2015年3期
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