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Multifunctional nanocomposites for image-guided cancer therapy are highly desired in clinical application.Herein,a novel theranostic agent based on gold and ferroferric oxide nanoparticles coating polypyrrole particles(PPy@Fe3O4/Au nanocomposites)for computed tomography(CT)and magnetic resonance(MR)imaging guided photothermal therapy was successfully assembled by a very facile electrostatic adsorption method.