2. 您的位置
3. 首页
4. 会议论文
5. Cholinergic Signaling Controls Learning and Memory via Mediating Dentate Neurogenesis in Depression

Cholinergic Signaling Controls Learning and Memory via Mediating Dentate Neurogenesis in Depression

来源 :第三届国际神经疾病大会暨2016脑网络与脑疾病高峰论坛 | 被引量 : 0次 | 上传用户：txzhang50

【摘 要】

：

The ability of learning and memory declines in all mammals during depression.This damage is caused by many cellular events involving the lesion of neurogenesis in dentate gyrus(DG)of the mammalian bra

【作 者】

：

Zhuoze Wu Huanhuan Yan Hao Li Lei Pei Youming Lu 

【机 构】

：

Department of Physiology,Tongji Medical College,Huazhong University of Science and Technology,430030

【出 处】

：

第三届国际神经疾病大会暨2016脑网络与脑疾病高峰论坛

【发表日期】

：

2016年10期

【关键词】

：

depression mice model neurogenesis acetylcholine brain-derived neurotrophic fact 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　The ability of learning and memory declines in all mammals during depression.This damage is caused by many cellular events involving the lesion of neurogenesis in dentate gyrus(DG)of the mammalian brain.

其他文献

Dopaminergic inputs in the dentate gyrus direct the choice of memory encoding

Rewarding experiences are often well remembered,and such memory formation is known to be dependent on dopamine modulation of the neural substrates engaged in learning and memory.Most studies character

会议

dopaminechannelrhodopsin-2theta oscillationtemporal difference learning

Acupuncture effect on pain and inflammasomes

会议

The link of tubular endoplasmic reticulum to neuritic dystrophy in Alzheimer's disease

会议

Downregulation of NAD-dependent deacetylase SIRT2 Protects Mouse Brain against Ischemic Stroke

Sirtuin 2(SIRT2)is a member of NAD+‐dependent protein deacetylases involved in a wide range of pathophysiological processes including myocardial injury,Parkinsons disease and Huntingtons disease.Howev

会议

Ischemic strokeSIRT2NeuronAGK2Middle cerebral artery occlusion

Targeted sequencing identifies 90 genes associated with neurodevelopmental disorders

Recently,several hundred candidate genes have emerged from whole‐exome sequencing studies for various neurodevelopmental disorders(NDDs).However,due to their individual low mutation frequency,it remai

会议

Autism spectrum disorderintellectual disabilitydevelopmental delaytargeted re

Synaptic Scaffold Proteins in Neuronal Signaling and Development

会议

Fear conditioning-induced autophagy contributes to memory consolidation via regulation of the surfac

Autophagy is important for the degradation of receptors,yet this degradation in learning and memory remains unknown.Auditory fear conditioning elicited autophagy in the amygdala and inhibition of auto

会议

AutophagyFear conditioningGABAARs

Novel functions of BK channels

会议

Caspase-1 knockout confers resilience to chronic stress via regulating the surface stability of AMPA

Inflammatory processes have been implicated in the pathophysiology of mood‐related disorders; however,whether caspase‐1,a classic inflammatory caspase,contributes to depression remains largely unknown

会议

Caspase-1Depression-like behaviorsAMPARs

Role of Cholinergic Neurons in Diagonal Band in Spatial Pattern Separation via Majorly Modulating Ne

Objective: local cholinergics neurons in junction of medial septum and diagonal band of broca(MS&DBB)regulate the newborn neurons in dorsal dentate gyrus(DG)via directly projection which impact spatia

会议

cholinergicjunction of MS&DBBnewborn neurondorsal dentate gyrusspatial patte