Background: We have recently identified and characterized a novel oncogene,maelstrom(MAEL)from 1q24,in the pathogenesis of hepatocellular carcinoma.In this study,MAEL was investigated for its oncogeni
Background: Although sunitinib is approved treatments in first-line therapy for patients with metastatic renal cell carcinoma(mRCC).In the second-line treatment choices consist of axitinib and everoli
Prostate cancer(PCa)is the leading cause of cancer related-death for both Western and Asian men.Precision oncology requires specific diagnosis markers for differential patients especially in various e
Hereditary leiomyomatosis and renal cell carcinoma-associated renal cell carcinoma is a rare and relatively newly defined entity.It has characteristic histological features and specific germline FH mu
MET(or c-MET)kinase signaling is aberrantly upregulated in many cancers and interacts with β-Catenin in cancer progression.We previously showed MET especially nuclear MET(nMET)triggers oncogenic signa
Gene signatures of metastasis could be population specific.Precision cancer therapy focuses on ethnic groups and individual patients.Here we applied big datasets based comparative protein-protein inte
Purpose:This study aimed to evaluate the effectiveness and safety of percutaneous hydrochloric acid enhanced radiofrequency ablation(HRFA)for large hepatocellular carcinoma(HCC)located in the caudate
Purpose: To evaluate the clinical efficacy and safety of transarterial embolization immedi ately followed by multiple thermal ablation in treatment of large hepatocellular carcino ma(HCC).Materials an
Background: Radiofrequency ablation(RFA)with hydrochloric acid(HCl)infusion caused extensive lesions in ex vivo porcine liver model.This study further evaluated the safety and efficacy of the method u