A Regulatory Factor Represses EV71 Genome Replication by Inhibiting Viral Polymerase and Attenuates

来源 :第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会 | 被引量 : 0次 | 上传用户:yangjianwu2008
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Enterovirus 71 (EV71) is a non-enveloped virus and possesses a single-stranded positive RNA genome,which contains a single ORF flanked by a 5untranslated region (5UTR) and a polyadenylated 3UTR.In this study,we initially demonstrated that EV71 infection activates the production of a regulatory factor,stimulates its activity,but represses the nucleus translocation of the protein.
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